dc.contributor.author | McLean, Mia A. | |
dc.contributor.author | Van den Bergh, Bea R.H. | |
dc.contributor.author | Baart, Martijn | |
dc.contributor.author | Vroomen, Jean | |
dc.contributor.author | van den Heuvel, Marion I. | |
dc.date.accessioned | 2020-07-03T09:33:28Z | |
dc.date.available | 2020-07-03T09:33:28Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Mia A. McLean, Bea R.H. Van den Bergh, Martijn Baart, Jean Vroomen, Marion I. van den Heuvel, The late positive potential (LPP): A neural marker of internalizing problems in early childhood, International Journal of Psychophysiology, Volume 155, 2020, Pages 78-86, ISSN 0167-8760, https://doi.org/10.1016/j.ijpsycho.2020.06.005. | es_ES |
dc.identifier.issn | 0167-8760 | |
dc.identifier.uri | http://hdl.handle.net/10810/45004 | |
dc.description | Available online 16 June 2020. | es_ES |
dc.description.abstract | Background: One potentially relevant neurophysiological marker of internalizing problems (anxiety/depressive
symptoms) is the late positive potential (LPP), as it is related to processing of emotional stimuli. For the first
time, to our knowledge, we investigated the value of the LPP as a neurophysiological marker for internalizing
problems and specific anxiety and depressive symptoms, at preschool age.
Method: At age 4 years, children (N=84) passively viewed a series of neutral, pleasant, and unpleasant pictures
selected from the International Affective Pictures System. Affective picture processing was measured via the LPP
(EEG recorded) and mothers reported on child behavior via the Child Behavior Checklist 1 ½ - 5 (internalizing,
DSM-anxiety, DSM-affective/depression subscales). Difference scores between the neutral and affective pictures
(i.e., neutral-pleasant and neutral-unpleasant) were computed for posterior, central and anterior brain locations
for early (300-700 ms), middle (700-1200 ms) and late (1200-2000 ms) time windows.
Results: Greater LPP difference scores for pleasant images in the anterior recording site, in the middle time
window, were associated with greater internalizing behaviors. Greater DSM-anxiety symptoms were associated
with greater LPP difference scores for unpleasant and pleasant images. After correcting for multiple testing, only
the association between greater DSM-affective/depression symptoms and greater LPP difference scores for unpleasant
images in the anterior recording site (early time window) remained significant.
Discussion: Our study has identified a potential neural marker of preschool internalizing problems. Children with
larger LPPs to unpleasant images may be at greater risk of internalizing problems, potentially due to an increased
emotional reactivity. | es_ES |
dc.description.sponsorship | The PELS study is supported by the national funding agencies of the
European Science Foundation (EuroSTRESS - PELS - 99930AB6-0CAC-
423B-9527-7487B33085F3) participating in the Eurocores Program
EuroSTRESS programme, i.e., the Brain and Cognition Programme of
the Netherlands Organisation for Scientific Research (NWO) for the
Netherlands. BVdB is project leader of the PELS study. BVdB was financially
supported by European Commission Seventh Framework
Programme (FP7—HEALTH. 2011.2.2.2-2 BRAINAGE, grant agreement
no: 279281). MvdH is supported by a Veni grant from the Dutch
Organization for Scientific Research (NWO; VI.Veni.191G.025). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | International Journal of Psychophysiology | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Late positive potential | es_ES |
dc.subject | EEG | es_ES |
dc.subject | Internalizing problems | es_ES |
dc.subject | Preschoolers | es_ES |
dc.title | The late positive potential (LPP): A neural marker of internalizing problems in early childhood | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license | es_ES |
dc.relation.publisherversion | https://www.sciencedirect.com/journal/international-journal-of-psychophysiology | es_ES |
dc.identifier.doi | 10.1016/j.ijpsycho.2020.06.005 | |