dc.contributor.author | Fuertes Sánchez, María | |
dc.contributor.author | Masdeu Margalef, Carme | |
dc.contributor.author | Martín Encinas, Endika | |
dc.contributor.author | Selas Lanseros, Asier | |
dc.contributor.author | Rubiales Alcaine, María Gloria | |
dc.contributor.author | Palacios Gambra, Francisco Javier | |
dc.contributor.author | Alonso Pérez, Concepción Estibaliz | |
dc.date.accessioned | 2020-08-04T11:06:27Z | |
dc.date.available | 2020-08-04T11:06:27Z | |
dc.date.issued | 2020-07-16 | |
dc.identifier.citation | Molecules 25(14) : (2020) // Article ID 3252 | es_ES |
dc.identifier.issn | 1420-3049 | |
dc.identifier.uri | http://hdl.handle.net/10810/45853 | |
dc.description.abstract | This review covers the synthesis and reactivity of 1,5-naphthyridine derivatives published in the last 18 years. These heterocycles present a significant importance in the field of medicinal chemistry because many of them exhibit a great variety of biological activities. First, the published strategies related to the synthesis of 1,5-naphthyridines are presented followed by the reactivity of these compounds with electrophilic or nucleophilic reagents, in oxidations, reductions, cross-coupling reactions, modification of side chains or formation of metal complexes. Finally, some properties and applications of these heterocycles studied during this period are examined. | es_ES |
dc.description.sponsorship | This research was funded by the Ministerio de Ciencia, Innovación y Universidades (MCIU), Agencia Estatal de Investigación (AEI), Fondo Europeo de Desarrollo Regional (FEDER; RTI2018-101818-B-I00, UE) and by Gobierno Vasco, Universidad del País Vasco (GV, IT 992-16; UPV). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.relation | info:eu-repo/grantAgreement/MCIU/RTI2018-101818-B-I00 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | 1,5-naphthyridines | es_ES |
dc.subject | heterocycle synthesis | es_ES |
dc.subject | metal complexes | es_ES |
dc.subject | biological activity | es_ES |
dc.title | Synthetic Strategies, Reactivity and Applications of 1,5-Naphthyridines | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2020-07-24T13:40:24Z | |
dc.rights.holder | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/) | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1420-3049/25/14/3252 | es_ES |
dc.identifier.doi | 10.3390/molecules25143252 | |
dc.departamentoes | Química orgánica I | |
dc.departamentoeu | Kimika organikoa I | |