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dc.contributor.authorSilventoinen, Karri
dc.contributor.authorJelenkovic Moreno, Aline
dc.contributor.authorSund, Reijo
dc.contributor.authorLatvala, Antti
dc.contributor.authorHonda, Chika
dc.contributor.authorInui, Fujio
dc.contributor.authorTomizawa, Rie
dc.contributor.authorWatanabe, Mikio
dc.contributor.authorSakai, Norio
dc.contributor.authorRebato Ochoa, Esther Matilde
dc.contributor.authorBusjahn, Andreas
dc.contributor.authorTyler, Jessica
dc.contributor.authorHopper, John L.
dc.contributor.authorOrdoñana Martín, Juan Ramón
dc.contributor.authorSánchez Romera, Juan Francisco
dc.contributor.authorColodro Conde, Lucía
dc.contributor.authorCalais Ferreira, Lucas
dc.contributor.authorOliveira, Vinicius C.
dc.contributor.authorFerreira, Pablo H.
dc.contributor.authorMedda, Emanuela
dc.contributor.authorNisticò, Lorenza
dc.contributor.authorToccaceli, Virgilia
dc.contributor.authorDerom, Catherine A.
dc.contributor.authorVlietinck, Robert F.
dc.contributor.authorLoos, Ruth J. F.
dc.contributor.authorSiribaddana, Sisira H.
dc.contributor.authorHotopf, Matthew
dc.contributor.authorSumathipala, Athula
dc.contributor.authorRijsdijk, Fruhling
dc.contributor.authorDuncan, Glen E.
dc.contributor.authorBuchwald, Dedra
dc.contributor.authorTynelius, Per
dc.contributor.authorRasmussen, Finn
dc.contributor.authorTan, Qihua
dc.contributor.authorZhang, Dongfeng
dc.contributor.authorPang, Zengchang
dc.contributor.authorMagnusson, Patrik K. E.
dc.contributor.authorPedersen, Nancy L.
dc.contributor.authorDahl Aslan, Anna K.
dc.contributor.authorHwang, Amie E.
dc.contributor.authorMack, Thomas M.
dc.contributor.authorKrueger, Robert F.
dc.contributor.authorMcGue, Matt
dc.contributor.authorPahlen, Shandell
dc.contributor.authorBrandt, Ingunn
dc.contributor.authorNilsen, Thomas S.
dc.contributor.authorHarris, Jennifer R.
dc.contributor.authorMartin, Nicholas G.
dc.contributor.authorMedland, Sarah E.
dc.contributor.authorMontgomery, Grant W.
dc.contributor.authorWillemsen, Gonneke
dc.contributor.authorBartels, Meike
dc.contributor.authorVan Beijsterveldt, Catharina E. M.
dc.contributor.authorFranz, Carol E.
dc.contributor.authorKremen, William S.
dc.contributor.authorLyons, Michael J.
dc.contributor.authorSilberg, Judy L.
dc.contributor.authorMaes, Hermine H.
dc.contributor.authorKandler, Christian
dc.contributor.authorNelson, Tracy L.
dc.contributor.authorWhitfield, Keith E.
dc.contributor.authorCorley, Robin P.
dc.contributor.authorHuibregtse, Brooke M.
dc.contributor.authorGatz, Margaret
dc.contributor.authorButler, David A.
dc.contributor.authorTarnoki, Adam D.
dc.contributor.authorTarnoki, David L.
dc.contributor.authorPark, Hang A.
dc.contributor.authorLee, Jooyeon
dc.contributor.authorLee, Soo Ji
dc.contributor.authorSung, Joohon
dc.contributor.authorYokoyama, Yoshie
dc.contributor.authorSørensen, Thorkild I. A.
dc.contributor.authorBoomsma, Dorret I.
dc.contributor.authorKaprio, Jaakko
dc.date.accessioned2020-11-26T10:39:14Z
dc.date.available2020-11-26T10:39:14Z
dc.date.issued2020-07-29
dc.identifier.citationScientific Reports 10 : (2020) // Article ID 12681es_ES
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/10810/48601
dc.description.abstractWe investigated the heritability of educational attainment and how it differed between birth cohorts and cultural-geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at 25 years of age or older. Genetic factors explained the major part of individual differences in educational attainment (heritability: a(2)=0.43; 0.41-0.44), but also environmental variation shared by co-twins was substantial (c(2)=0.31; 0.30-0.33). The proportions of educational variation explained by genetic and shared environmental factors did not differ between Europe, North America and Australia, and East Asia. When restricted to twins 30 years or older to confirm finalized education, the heritability was higher in the older cohorts born in 1900-1949 (a(2)=0.44; 0.41-0.46) than in the later cohorts born in 1950-1989 (a(2)=0.38; 0.36-0.40), with a corresponding lower influence of common environmental factors (c(2)=0.31; 0.29-0.33 and c(2)=0.34; 0.32-0.36, respectively). In conclusion, both genetic and environmental factors shared by co-twins have an important influence on individual differences in educational attainment. The effect of genetic factors on educational attainment has decreased from the cohorts born before to those born after the 1950s.es_ES
dc.description.sponsorshipThis study was conducted within the CODATwins project. We thank Wendy Cozen, University of Southern California, for sharing data with us. Funding for collaborators: Netherlands Twin Register acknowledges the Netherlands Organization for Scientific Research (NWO) and MagW/ZonMW grants 904-61-090, 985-10-002, 912-10-020, 904-61-193,480-04-004, 463-06-001, 451-04-034, 400-05-717, Addiction-31160008, Middelgroot-911-09-032, Spinozapremie 56-464-14192; VU University's Institute for Health and Care Research (EMGO+); the European Research Council (ERC - 230374), the Avera Institute, Sioux Falls, South Dakota (USA). Data collection and analyses in Finnish twin cohorts have been supported by ENGAGE - European Network for Genetic and Genomic Epidemiology, FP7-HEALTH-F4-2007, Grant Agreement Number 201413, National Institute of Alcohol Abuse and Alcoholism (Grants AA-12502, AA-00145, and AA-09203 to R J Rose, the Academy of Finland Center of Excellence in Complex Disease Genetics (Grant Numbers: 213506, 129680), and the Academy of Finland (Grants 100499, 205585, 118555, 141054, 265240, 263278 and 264146 to J Kaprio). Since its origin the East Flanders Prospective Survey has been partly supported by grants from the Fund of Scientific Research, Flanders and Twins, a non-profit Association for Scientific Research in Multiple Births (Belgium). Anthropometric measurements of the Hungarian twins were supported by Medexpert Ltd., Budapest, Hungary. The Murcia Twin Registry is supported by Fundacion Seneca, Regional Agency for Science and Technology, Murcia, Spain (08633/PHCS/08, 15302/PHCS/10 & 19479/PI/14) and Ministry of Science and Innovation, Spain (PSI2009-11560 & PSI2014-56680-R). K Silventoinen is supported by Osaka University's International Joint Research Promotion Program. We acknowledge The Swedish Twin Registry for access to data. The Swedish Twin Registry is managed by Karolinska Institutet and receives funding through the Swedish Research Council under the grant no 2017-00641. This research was facilitated through access to Twins Research Australia, a national resource supported by a Centre of Research Excellence Grant (ID: 1079102), from the National Health and Medical Research Council. California Twin Program was supported by The California Tobacco-Related Disease Research Program (7RT-0134H, 8RT-0107H, 6RT-0354H) and the National Institutes of Health (1R01ESO15150-01). The Carolina African American Twin Study of Aging (CAATSA) was funded by a grant from the National Institute on Aging (grant 1RO1-AG13662-01A2) to K. E. Whitfield. Colorado Twin Registry is funded by NIDA funded center grant DA011015, & Longititudinal Twin Study HD10333; Author Huibregtse is supported by 5T32DA017637 and 5T32AG052371. Washington State Twin Registry (formerly the University of Washington Twin Registry) was supported in part by grant NIH RC2 HL103416 (D. Buchwald, PI). Vietnam Era Twin Study of Aging was supported by National Institute of Health grants NIA R01 AG018384, R01 AG018386, R01 AG022381, and R01 AG022982, and, in part, with resources of the VA San Diego Center of Excellence for Stress and Mental Health. The Cooperative Studies Program of the Office of Research & Development of the United States Department of Veterans Affairs has provided financial support for the development and maintenance of the Vietnam Era Twin (VET) Registry. The content of this manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the NIA/NIH, or the VA. The NAS-NRC Twin Registry acknowledges financial support from the National Institutes of Health grant number R21 AG039572. Korean Twin-Family Register was supported by the Global Research Network Program of the National Research Foundation (NRF 2011-220-E00006). Osaka University Aged Twin Registry is supported by grants from JSPS KAKENHI JP (23593419, 24792601, 26671010, 24590695, 26293128, 16K15385, 16K15978, 16K15989, 16H03261).es_ES
dc.language.isoenges_ES
dc.publisherNaturees_ES
dc.relationinfo:eu-repo/grantAgreement/MCIU/PSI2009-11560es_ES
dc.relationinfo:eu-repo/grantAgreement/MCIU/PSI2014-56680-Res_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectcognitive-abilityes_ES
dc.subjectheritabilityes_ES
dc.subjectmetaanalysises_ES
dc.subjectinequalityes_ES
dc.subjectphenotypees_ES
dc.subjecttraitses_ES
dc.titleGenetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohortses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holderThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creat iveco mmons .org/licen ses/by/4.0/es_ES
dc.rights.holderAtribución 3.0 España*
dc.relation.publisherversionhttps://www.nature.com/articles/s41598-020-69526-6es_ES
dc.identifier.doi10.1038/s41598-020-69526-6
dc.departamentoesFisiologíaes_ES
dc.departamentoeuFisiologiaes_ES


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This  article  is  licensed  under  a  Creative  Commons  Attribution  4.0  International  License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format,  as  long  as  you  give  appropriate  credit  to  the  original  author(s)  and  the  source,  provide  a  link  to  the  Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.  If  material  is  not  included  in  the  article’s  Creative  Commons  license  and  your  intended  use  is  not  permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creat iveco mmons .org/licen ses/by/4.0/
Except where otherwise noted, this item's license is described as This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creat iveco mmons .org/licen ses/by/4.0/