dc.contributor.author | Lizarazu, Mikel | |
dc.contributor.author | Lallier, Marie | |
dc.contributor.author | Bourguignon, Mathieu | |
dc.contributor.author | Carreiras, Manuel | |
dc.contributor.author | Molinaro, Nicola | |
dc.date.accessioned | 2021-02-08T09:10:43Z | |
dc.date.available | 2021-02-08T09:10:43Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Mikel Lizarazu, Marie Lallier, Mathieu Bourguignon, Manuel Carreiras, Nicola Molinaro, Impaired neural response to speech edges in dyslexia, Cortex, Volume 135, 2021, Pages 207-218, ISSN 0010-9452, https://doi.org/10.1016/j.cortex.2020.09.033. | es_ES |
dc.identifier.issn | 0010-9452 | |
dc.identifier.uri | http://hdl.handle.net/10810/50087 | |
dc.description | Available online 10 December 2020 | es_ES |
dc.description.abstract | Speech comprehension has been proposed to critically rely on oscillatory cortical tracking, that is, phase alignment of neural oscillations to the slow temporal modulations (envelope) of speech. Speech-brain entrainment is readjusted over time as transient events (edges) in speech lead to speech-brain phase realignment. Auditory behavioral research suggests that phonological deficits in dyslexia are linked to difficulty in discriminating speech edges. Importantly, research to date has not specifically examined neural responses to speech edges in dyslexia. In the present study, we used MEG to record brain activity from normal and dyslexic readers while they listened to speech. We computed phase locking values (PLVs) to evaluate phase entrainment between neural oscillations and the speech envelope time-locked to edge onsets. In both groups, we observed that edge onsets induced phase resets in the auditory oscillations tracking speech, thereby enhancing their entrainment to speech. Importantly, dyslexic readers showed weaker PLVs compared to normal readers in left auditory regions from ~.15 sec to ~.65 sec after edge onset. Our results indicate that the neural mechanism that adapts cortical entrainment to the speech envelope is impaired in dyslexia. These findings here are consistent with the temporal sampling theory of developmental dyslexia. | es_ES |
dc.description.sponsorship | This work was supported by: the Basque Government through
the BERC 2018e2021 program and by the Spanish State
Research Agency through BCBL Severo Ochoa excellence
accreditation SEV-2015-0490. The Spanish Ministry of Science
and Innovation (CONSOLIDER-INGENIO2010 and CSD2008-
00048 to M.C.), the European Research Council (ERC-2011-
ADG-295362 to M.C.), the Spanish Ministry of Economy and
Competitiveness, Programme d’investissements d’avenir
(ANR-10-LABX-0087 and ANR-10-IDEX-0001-02 to M.L), the
Agencia Estatal de Investigaci on, the Fondo Europeo de
Desarrollo Regional (PSI2012-32128 to M.L., PSI2016-77175-P to
M.B., PSI2015-67353-R to M.C., RTI2018-096311-B-I00 to N.M.),
and Innoviris (grant Attract 2015-BB2B-10 to M.B.). The BCBL
acknowledges funding from Ayuda Centro de Excelencia
Severo Ochoa SEV-2015-0490 from the MINECO | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | ScienceDirect | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/SEV-2015-0490 | es_ES |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/ERC-2011-ADG-295362 | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/PSI2015-67353-R | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/RTI2018-096311-B-I00 | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/PSI2012-32128 | |
dc.relation | info:eu-repo/grantAgreement/MINECO/PSI2016-77175-P | |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Dyslexia | es_ES |
dc.subject | Phonological deficit | es_ES |
dc.subject | Speech | es_ES |
dc.subject | Neural oscillations | es_ES |
dc.subject | Magnetoencephalography | es_ES |
dc.title | Impaired neural response to speech edges in dyslexia | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2020 Elsevier Ltd. All rights reserved. | es_ES |
dc.relation.publisherversion | https://www.sciencedirect.com/journal/cortex | es_ES |
dc.identifier.doi | 10.1016/j.cortex.2020.09.033 | |