Quantification of Biomarker Functionality Predicts Patient Outcomes

Larijani, Banafshé; Miles, James; Ward, Stephen G.; Parker, Peter J.

dc.contributor.author	Larijani, Banafshé
dc.contributor.author	Miles, James
dc.contributor.author	Ward, Stephen G.
dc.contributor.author	Parker, Peter J.
dc.date.accessioned	2021-06-16T11:08:56Z
dc.date.available	2021-06-16T11:08:56Z
dc.date.issued	2021-05-11
dc.identifier.citation	British Journal Of Cancer 124(10) : 1618-1620 (2021)	es_ES
dc.identifier.issn	0007-0920
dc.identifier.issn	1532-1827
dc.identifier.uri	http://hdl.handle.net/10810/51918
dc.description.abstract	Implementation of a quantitative molecular imaging method (iFRET), which determines receptor–ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to those with a high level of interaction.	es_ES
dc.description.sponsorship	The original research was supported, in part, by Department of Education, Basque Government-IT1270-19, Elkartek grant (BG18) and the Spanish Ministry grant (MINECO) PROJECTS of EXCELLENCE (BFU2015-65625-P). P.J.P. was supported by a core grant to the Francis Crick Institute, from Cancer Research UK (FC001130), the UK Medical Research Council (FC001130) and the Wellcome Trust (FC001130).	es_ES
dc.language.iso	eng	es_ES
dc.publisher	Springer Nature	es_ES
dc.relation	info:eu-repo/grantAgreement/MINECO/BFU2015-65625-P	es_ES
dc.rights	info:eu-repo/semantics/openAccess	es_ES
dc.rights.uri	http://creativecommons.org/licenses/by/3.0/es/	*
dc.subject	quantitative molecular imaging	es_ES
dc.subject	malignant neoplastic diseases	es_ES
dc.subject	Immune-checkpoints	es_ES
dc.title	Quantification of Biomarker Functionality Predicts Patient Outcomes	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.rights.holder	This article is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0)	es_ES
dc.rights.holder	Atribución 3.0 España	*
dc.relation.publisherversion	https://www.nature.com/articles/s41416-021-01291-3	es_ES
dc.identifier.doi	10.1038/s41416-021-01291-3
dc.departamentoes	Bioquímica y biología molecular	es_ES
dc.departamentoeu	Biokimika eta biologia molekularra	es_ES

Files in this item

Name:: license_rdf
Size:: 914bytes
Format:: application/rdf+xml

View/Open

Name:: s41416-021-01291-3.pdf
Size:: 506.1Kb
Format:: PDF
Description:: Artículo principal

View/Open

This item appears in the following Collection(s)

Artículos

Show simple item record

This article is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0)

Except where otherwise noted, this item's license is described as This article is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0)