Metastasis, an Example of Evolvability
dc.contributor.author | Laruelle, Annick | |
dc.contributor.author | Manini, Claudia | |
dc.contributor.author | Iñarra García, María Elena | |
dc.contributor.author | López Fernández de Villaverde, José Ignacio | |
dc.date.accessioned | 2021-08-09T08:24:26Z | |
dc.date.available | 2021-08-09T08:24:26Z | |
dc.date.issued | 2021-06-21 | |
dc.identifier.citation | Cancers 13(15) : (2021) // Article ID 3653 | es_ES |
dc.identifier.issn | 2072-6694 | |
dc.identifier.uri | http://hdl.handle.net/10810/52779 | |
dc.description.abstract | This overview focuses on two different perspectives to analyze the metastatic process taking clear cell renal cell carcinoma as a model, molecular and ecological. On the one hand, genomic analyses have demonstrated up to seven different constrained routes of tumor evolution and two different metastatic patterns. On the other hand, game theory applied to cell encounters within a tumor provides a sociological perspective of the possible behaviors of individuals (cells) in a collectivity. This combined approach provides a more comprehensive understanding of the complex rules governing a neoplasm. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | |
dc.subject | cancer | es_ES |
dc.subject | metastasis | es_ES |
dc.subject | genomic analysis | es_ES |
dc.subject | microenvironment | es_ES |
dc.subject | tumor ecology | es_ES |
dc.subject | game theory | es_ES |
dc.title | Metastasis, an Example of Evolvability | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2021-08-06T15:19:10Z | |
dc.rights.holder | 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/2072-6694/13/15/3653/htm | es_ES |
dc.identifier.doi | 10.3390/cancers13153653 | |
dc.departamentoes | Análisis Económico | |
dc.departamentoeu | Analisi Ekonomikoa |
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Except where otherwise noted, this item's license is described as 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).