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dc.contributor.authorLaruelle, Annick ORCID
dc.contributor.authorManini, Claudia
dc.contributor.authorIñarra García, María Elena ORCID
dc.contributor.authorLópez Fernández de Villaverde, José Ignacio ORCID
dc.date.accessioned2021-08-09T08:24:26Z
dc.date.available2021-08-09T08:24:26Z
dc.date.issued2021-06-21
dc.identifier.citationCancers 13(15) : (2021) // Article ID 3653es_ES
dc.identifier.issn2072-6694
dc.identifier.urihttp://hdl.handle.net/10810/52779
dc.description.abstractThis overview focuses on two different perspectives to analyze the metastatic process taking clear cell renal cell carcinoma as a model, molecular and ecological. On the one hand, genomic analyses have demonstrated up to seven different constrained routes of tumor evolution and two different metastatic patterns. On the other hand, game theory applied to cell encounters within a tumor provides a sociological perspective of the possible behaviors of individuals (cells) in a collectivity. This combined approach provides a more comprehensive understanding of the complex rules governing a neoplasm.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/
dc.subjectcanceres_ES
dc.subjectmetastasises_ES
dc.subjectgenomic analysises_ES
dc.subjectmicroenvironmentes_ES
dc.subjecttumor ecologyes_ES
dc.subjectgame theoryes_ES
dc.titleMetastasis, an Example of Evolvabilityes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.date.updated2021-08-06T15:19:10Z
dc.rights.holder2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).es_ES
dc.relation.publisherversionhttps://www.mdpi.com/2072-6694/13/15/3653/htmes_ES
dc.identifier.doi10.3390/cancers13153653
dc.departamentoesAnálisis Económico
dc.departamentoeuAnalisi Ekonomikoa


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2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).