dc.contributor.author | Caffarra, Sendy | |
dc.contributor.author | Joo, Sung Jun | |
dc.contributor.author | Bloom, David | |
dc.contributor.author | Kruper, John | |
dc.contributor.author | Rokem, Ariel | |
dc.contributor.author | Yeatman, Jason D. | |
dc.date.accessioned | 2021-11-04T08:41:18Z | |
dc.date.available | 2021-11-04T08:41:18Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Caffarra, S., Joo, S. J., Bloom, D., Kruper, J., Rokem, A., & Yeatman, J. D. (2021). Development of the visual white matter pathways mediates development of electrophysiological responses in visual cortex. Human Brain Mapping, 42( 17), 5785– 5797. https://doi.org/10.1002/hbm.25654 | es_ES |
dc.identifier.issn | 1065-9471 | |
dc.identifier.uri | http://hdl.handle.net/10810/53702 | |
dc.description | First published: 06 September 2021 | es_ES |
dc.description.abstract | The latency of neural responses in the visual cortex changes systematically across
the lifespan. Here, we test the hypothesis that development of visual white matter
pathways mediates maturational changes in the latency of visual signals. Thirty-eight
children participated in a cross-sectional study including diffusion magnetic resonance
imaging (MRI) and magnetoencephalography (MEG) sessions. During the MEG
acquisition, participants performed a lexical decision and a fixation task on words
presented at varying levels of contrast and noise. For all stimuli and tasks, early
evoked fields were observed around 100 ms after stimulus onset (M100), with slower
and lower amplitude responses for low as compared to high contrast stimuli. The
optic radiations and optic tracts were identified in each individual's brain based on
diffusion MRI tractography. The diffusion properties of the optic radiations predicted
M100 responses, especially for high contrast stimuli. Higher optic radiation fractional
anisotropy (FA) values were associated with faster and larger M100 responses. Over
this developmental window, the M100 responses to high contrast stimuli became
faster with age and the optic radiation FA mediated this effect. These findings suggest
that the maturation of the optic radiations over childhood accounts for individual
variations observed in the developmental trajectory of visual cortex responses. | es_ES |
dc.description.sponsorship | H2020 Marie Skłodowska-Curie Actions,
Grant/Award Number: 837228; Italian
Ministry of University and Research (MIUR):
Programma Rita Levi Montalcini; Jacobs
Foundation Research Fellowship, Grant/Award
Number: RF1MH121868-01; National
Institute of Child Health and Human
Development, Grant/Award Numbers:
R01HD09586101, R21HD092771; National
Research Foundation of Korea, Grant/Award
Number: NRF-2019R1C1C1009383; NSF/
BSF, Grant/Award Number: BCS #1551330 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Human Brain Mapping | es_ES |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/MC/837228 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | childhood | es_ES |
dc.subject | diffusion MRI | es_ES |
dc.subject | MEG | es_ES |
dc.subject | tractography | es_ES |
dc.subject | visual system | es_ES |
dc.title | Development of the visual white matter pathways mediates development of electrophysiological responses in visual cortex | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any
medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
© 2021 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. | es_ES |
dc.relation.publisherversion | https://onlinelibrary.wiley.com/journal/10970193 | es_ES |
dc.identifier.doi | 10.1002/hbm.25654 | |