Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model

Stephens, Maialen; López Linares, Karen; Aldazabal Rego, Javier; Macías García, Iratxe; Ortuzar Markes, Naiara; Bengoetxea Odriozola, Harkaitz; Bulnes Sesma, Susana; Alcorta Sevillano, Natividad; Infante, Arantza; Lafuente Sánchez, José Vicente; Rodríguez, Clara I.

dc.contributor.author	Stephens, Maialen
dc.contributor.author	López Linares, Karen
dc.contributor.author	Aldazabal Rego, Javier
dc.contributor.author	Macías García, Iratxe
dc.contributor.author	Ortuzar Markes, Naiara
dc.contributor.author	Bengoetxea Odriozola, Harkaitz
dc.contributor.author	Bulnes Sesma, Susana
dc.contributor.author	Alcorta Sevillano, Natividad
dc.contributor.author	Infante, Arantza
dc.contributor.author	Lafuente Sánchez, José Vicente
dc.contributor.author	Rodríguez, Clara I.
dc.date.accessioned	2021-11-09T11:31:06Z
dc.date.available	2021-11-09T11:31:06Z
dc.date.issued	2021-09-15
dc.identifier.citation	Scientific Data 8(1) : (2021) // Article ID 240	es_ES
dc.identifier.issn	2052-4463
dc.identifier.uri	http://hdl.handle.net/10810/53714
dc.description.abstract	The development of new effective and safer therapies for osteoporosis, in addition to improved diagnostic and prevention strategies, represents a serious need in the scientific community. Micro-CT image-based analyses in association with biomechanical testing have become pivotal tools in identifying osteoporosis in animal models by assessment of bone microarchitecture and resistance, as well as bone strength. Here, we describe a dataset of micro-CT scans and reconstructions of 15 whole femurs and biomechanical tests on contralateral femurs from C57BL/6JOlaHsd ovariectomized (OVX), resembling human post-menopausal osteoporosis, and sham operated (sham) female mice. Data provided for each mouse include: the acquisition images (.tiff), the reconstructed images (.bmp) and an.xls file containing the maximum attenuations for each reconstructed image. Biomechanical data include an.xls file with the recorded load-displacement, a movie with the filmed test and an.xls file collecting all biomechanical results.	es_ES
dc.description.sponsorship	This study was funded by Basque Country government under the ELKARTEK program No. kk-2018/00031/BC and No. kk-2019/00093/BC.	es_ES
dc.language.iso	eng	es_ES
dc.publisher	Nature Research	es_ES
dc.rights	info:eu-repo/semantics/openAccess	es_ES
dc.rights.uri	http://creativecommons.org/licenses/by/3.0/es/	*
dc.subject	bone	es_ES
dc.title	Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.rights.holder	Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.	es_ES
dc.rights.holder	Atribución 3.0 España	*
dc.relation.publisherversion	https://www.nature.com/articles/s41597-021-01012-8#Sec1	es_ES
dc.identifier.doi	10.1038/s41597-021-01012-8
dc.departamentoes	Neurociencias	es_ES
dc.departamentoeu	Neurozientziak	es_ES

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Except where otherwise noted, this item's license is described as Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.