External surface anatomy of the postfolding human embryo: Computer-aided, three-dimensional reconstruction of printable digital specimens
dc.contributor.author | Azkue Barrenetxea, Jon Jatsu | |
dc.date.accessioned | 2022-01-12T09:19:24Z | |
dc.date.available | 2022-01-12T09:19:24Z | |
dc.date.issued | 2021-12 | |
dc.identifier.citation | Journal of Anatomy 239(6) : 1438-1451 (2021) | es_ES |
dc.identifier.issn | 0021-8782 | |
dc.identifier.issn | 1469-7580 | |
dc.identifier.uri | http://hdl.handle.net/10810/54912 | |
dc.description.abstract | Opportunities for clinicians, researchers, and medical students to become acquainted with the three-dimensional (3D) anatomy of the human embryo have historically been limited. This work was aimed at creating a collection of digital, printable 3D surface models demonstrating major morphogenetic changes in the embryo's external anatomy, including typical features used for external staging. Twelve models were digitally reconstructed based on optical projection tomography, high-resolution episcopic microscopy and magnetic resonance imaging datasets of formalin-fixed specimens of embryos of developmental stages 12 through 23, that is, stages following longitudinal and transverse embryo folding. The reconstructed replica reproduced the external anatomy of the actual specimens in great detail, and the progress of development over stages was recognizable in a variety of external anatomical features and bodily structures, including the general layout and curvature of the body, the pharyngeal arches and cervical sinus, the physiological gut herniation, and external genitalia. In addition, surface anatomy features commonly used for embryo staging, such as distinct steps in the morphogenesis of facial primordia and limb buds, were also apparent. These digital replica, which are all provided for 3D visualization and printing, can serve as a novel resource for teaching and learning embryology and may contribute to a better appreciation of the human embryonic development. | es_ES |
dc.language.iso | eng | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | 3D graphics | es_ES |
dc.subject | developmental stages | es_ES |
dc.subject | human embryo | es_ES |
dc.subject | surface rendering | es_ES |
dc.subject | developmental-stages | es_ES |
dc.subject | 1st trimester | es_ES |
dc.subject | 3D | es_ES |
dc.subject | education | es_ES |
dc.subject | models | es_ES |
dc.subject | atlas | es_ES |
dc.title | External surface anatomy of the postfolding human embryo: Computer-aided, three-dimensional reconstruction of printable digital specimens | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | This is an open access article under the terms of the Creative Commons Attributio n- NonCommerc ial- NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.© 2021 The Authors. Journal of Anatomy published by John Wiley & Sons Ltd on behalf of Anatomical Society | es_ES |
dc.rights.holder | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.relation.publisherversion | https://onlinelibrary.wiley.com/doi/10.1111/joa.13514 | es_ES |
dc.identifier.doi | 10.1111/joa.13514 | |
dc.departamentoes | Neurociencias | es_ES |
dc.departamentoeu | Neurozientziak | es_ES |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's license is described as This is an open access article under the terms of the Creative Commons Attributio n- NonCommerc ial- NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.© 2021 The Authors. Journal of Anatomy published by John Wiley & Sons Ltd on behalf of Anatomical Society