Antimicrobial Peptides with Anti-Candida Activity
dc.contributor.author | Pérez Rodríguez, Aitzol | |
dc.contributor.author | Eraso Barrio, María Elena | |
dc.contributor.author | Quindós Andrés, Guillermo | |
dc.contributor.author | Mateo Alesanco, Estibaliz | |
dc.date.accessioned | 2022-08-31T06:50:33Z | |
dc.date.available | 2022-08-31T06:50:33Z | |
dc.date.issued | 2022-08-17 | |
dc.identifier.citation | International Journal of Molecular Sciences 23(16) : (2022) // Article ID 9264 | es_ES |
dc.identifier.issn | 1422-0067 | |
dc.identifier.uri | http://hdl.handle.net/10810/57357 | |
dc.description.abstract | [EN] Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is the most usual, presenting a high morbidity and mortality. Candida albicans remains the prevalent etiologic agent, but the incidence of other species such as Candida parapsilosis, Candida glabrata and Candida auris keeps increasing. These pathogens frequently show a reduced susceptibility to commonly used antifungal drugs, including polyenes, triazoles and echinocandins, and the incidence of emerging multi-drug-resistant strains of these species continues to increase. Therefore, the need to search for new molecules that target these pathogenic species in a different manner is now more urgent than ever. Nature is an almost endless source of interesting new molecules that could meet this need. Among these molecules, antimicrobial peptides, present in different sources in nature, possess some advantages over conventional antifungal agents, even with their own drawbacks, and are considered as a promising pharmacological option against a wide range of microbial infections. In this review, we describe 20 antimicrobial peptides from different origins that possess an activity against Candida. | es_ES |
dc.description.sponsorship | This research was funded by the Spanish Ministry of Science and Innovation (PID2020-117983RB-I00) and by the Consejería de Educación, Universidades e Investigación of Gobierno Vasco-Eusko Jaurlaritza (IT1607-22). A.P.-R. was funded by a Ph.D. grant from the University of the Basque Country (PIF17/167). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/PID2020-117983RB-I00 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | fungal infections | es_ES |
dc.subject | candidiasis | es_ES |
dc.subject | microbial resistance | es_ES |
dc.subject | antifungal peptides | es_ES |
dc.title | Antimicrobial Peptides with Anti-Candida Activity | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2022-08-25T11:19:45Z | |
dc.rights.holder | © 2022 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1422-0067/23/16/9264 | es_ES |
dc.identifier.doi | 10.3390/ijms23169264 | |
dc.departamentoes | Inmunología, microbiología y parasitología | |
dc.departamentoeu | Immunologia, mikrobiologia eta parasitologia |
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Except where otherwise noted, this item's license is described as © 2022 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).