dc.contributor.author | Fraga Jesús, Nadezhna | |
dc.contributor.author | Benito Fernández, Denis ![ORCID](/themes/Mirage2//images/orcid_16x16.png) | |
dc.contributor.author | Briaudeau, Tifanie | |
dc.contributor.author | Izaguirre Aramayona, Urtzi | |
dc.contributor.author | Ruiz Rodríguez, Pamela | |
dc.date.accessioned | 2022-10-28T17:50:30Z | |
dc.date.available | 2022-10-28T17:50:30Z | |
dc.date.issued | 2022-11 | |
dc.identifier.citation | Chemosphere 307(4) : (2022) // Article ID 136022 | es_ES |
dc.identifier.issn | 0045-6535 | |
dc.identifier.issn | 1879-1298 | |
dc.identifier.uri | http://hdl.handle.net/10810/58219 | |
dc.description.abstract | The rising use of lithium (Li) in industrial processes, modern technology and medicine has generated concerns in the scientific community, in particular its potential impact on the environment. Unfortunately, there is only scarce information concerning the toxicity of lithium in marine organisms. The objective of this study is to determine the toxicity of Li using Mytilus galloprovincialis as model organism, based on acute and sublethal toxicity tests. In the first experiment, mussels were exposed for 9 days to a range of acute concentrations of Li (0, 2, 5, 13, 34, 89, 233 and 610 mg/L Li) in order to find the median lethal concentration. In the sublethal experiment, mussels were exposed to environmentally relevant concentrations of Li (0, 0.1, 1, 10 mg/L Li) for 21 days. Digestive gland and gonad samples were taken at day 0, 1, 7 and 21 for histopathological analysis. Samples of the whole mussels were taken for chemical analysis at day 0 and after 21 days. Results showed that M. gal-loprovincialis had a LC50 value of 153 mg/L Li after 9 days of exposure. Lower concentrations (environmentally relevant), led to Li bioaccumulation in a dose-dependent manner and histopathological effects in a time -dependent manner. Atrophy of the digestive alveoli epithelium and degeneration of the digestive gland were observed after 21 days of exposure. These findings open new perspectives for the understanding of the toxic effects of Li on marine organisms and evidence the need for further long-term research at different levels of biological organizations. | es_ES |
dc.description.sponsorship | This work was funded by the Basque Government (Grant to Consolidated Research Group, CBET, IT1302-19) . SGIker technical and human support (UPV/EHU, MICINN, GV/EJ, ESF) is gratefully acknowledged. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | lithium | es_ES |
dc.subject | Mytilus galloprovincialis | es_ES |
dc.subject | acute toxicity | es_ES |
dc.subject | histopathology | es_ES |
dc.subject | sublethal toxicity | es_ES |
dc.subject | bioaccumulation | es_ES |
dc.title | Toxicopathic effects of lithium in mussels | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | es_ES |
dc.rights.holder | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0045653522025152?via%3Dihub | es_ES |
dc.identifier.doi | 10.1016/j.chemosphere.2022.136022 | |
dc.departamentoes | Zoología y biología celular animal | es_ES |
dc.departamentoeu | Zoologia eta animalia zelulen biologia | es_ES |