Influence of rGO on the Crystallization Kinetics, Cytoxicity, and Electrical and Mechanical Properties of Poly (L-lactide-co-ε-caprolactone) Scaffolds
dc.contributor.author | Díaz Tajada, Esperanza | |
dc.contributor.author | León, Joseba | |
dc.contributor.author | Murillo Marrodán, Alberto | |
dc.contributor.author | Ribeiro, Sylvie | |
dc.contributor.author | Lanceros Méndez, Senentxu | |
dc.date.accessioned | 2022-11-16T18:50:07Z | |
dc.date.available | 2022-11-16T18:50:07Z | |
dc.date.issued | 2022-10-23 | |
dc.identifier.citation | Materials 15(21) : (2022) // Article ID 7436 | es_ES |
dc.identifier.issn | 1996-1944 | |
dc.identifier.uri | http://hdl.handle.net/10810/58381 | |
dc.description.abstract | Biodegradable scaffolds of poly (L-lactide-co-ε-caprolactone) (PLCL) and reduced graphene oxide (rGO) were prepared by TIPS (thermally induced phase separation). The nonisothermal cold crystallization kinetics were investigated by differential scanning calorimetry (DSC) with various cooling rates. The experimental values indicate that nonisothermal crystallization improves with cooling rate, but the increasing rGO concentration delays crystallization at higher temperatures. The activation energies were calculated by the Kissinger equation; the values were very similar for PLCL and for its compounds with rGO. The electrical conductivity measurements show that the addition of rGO leads to a rapid transition from insulating to conductive scaffolds with a percolation value of ≈0.4 w/w. Mechanical compression tests show that the addition of rGO improves the mechanical properties of porous substrates. In addition, it is an anisotropic material, especially at compositions of 1% w/w of rGO. All of the samples with different rGO content up to 1% are cytotoxic for C2C12 myoblast cells. | es_ES |
dc.description.sponsorship | This work was supported by the University of The Basque Center. The authors acknowledge funding by Spanish State Research Agency (AEI) and the European Regional Development Fund (ERFD) through the project PID2019-106099RB-C43/AEI/10.13039/501100011033 and from the Basque Government Industry Departments under the ELKARTEK program. This work has been also supported by FCT–Fundação para a Ciência e Tecnologia (FCT) under the scope of the strategic funding of UID/FIS/04650/2020 and UIDB/04469/2020 units and project PTDC/BTM-MAT/28237/2017. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/PID2019-106099RB-C43 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | PLCL/rGO | es_ES |
dc.subject | scaffolds | es_ES |
dc.subject | crystallization | es_ES |
dc.subject | electrical properties | es_ES |
dc.subject | mechanical properties | es_ES |
dc.subject | cytotoxicity | es_ES |
dc.title | Influence of rGO on the Crystallization Kinetics, Cytoxicity, and Electrical and Mechanical Properties of Poly (L-lactide-co-ε-caprolactone) Scaffolds | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2022-11-10T14:27:50Z | |
dc.rights.holder | © 2022 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1996-1944/15/21/7436 | es_ES |
dc.identifier.doi | 10.3390/ma15217436 | |
dc.departamentoes | Ingeniería Minera y Metalúrgica y Ciencia de los Materiales | |
dc.departamentoeu | Meatze eta metalurgia ingeniaritza materialen zientzia |
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Except where otherwise noted, this item's license is described as © 2022 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).