dc.contributor.author | Ahovan, Zahra Aliakbar | |
dc.contributor.author | Esmaeili, Zahra | |
dc.contributor.author | Eftekhari, Behnaz Sadat | |
dc.contributor.author | Khosravimelal, Sadjad | |
dc.contributor.author | Alehosseini, Morteza | |
dc.contributor.author | Orive Arroyo, Gorka | |
dc.contributor.author | Dolatshahi-Pirouz, Alireza | |
dc.contributor.author | Chauhan, Narendra Pal Singh | |
dc.contributor.author | Janmey, Paul A. | |
dc.contributor.author | Hashemi, Ali | |
dc.contributor.author | Kundu, Subhas C. | |
dc.contributor.author | Gholipourmalekabadi, Mazaher | |
dc.date.accessioned | 2023-01-17T19:11:32Z | |
dc.date.available | 2023-01-17T19:11:32Z | |
dc.date.issued | 2022-12 | |
dc.identifier.citation | Materials Today Bio 17 : (2022) // Article ID 100499 | es_ES |
dc.identifier.issn | 2590-0064 | |
dc.identifier.uri | http://hdl.handle.net/10810/59343 | |
dc.description.abstract | Millions of people die annually due to uncured wound infections. Healthcare systems incur high costs to treat wound infections. Tt is predicted to become more challenging due to the rise of multidrug-resistant conditions. During the last decades, smart antibacterial hydrogels could attract attention as a promising solution, especially for skin wound infections. These antibacterial hydrogels are termed 'smart' due to their response to specific physical and chemical environmental stimuli. To deliver different drugs to particular sites in a controlled manner, various types of crosslinking strategies are used in the manufacturing process. Smart hydrogels are designed to provide antimicrobial agents to the infected sites or are built from polymers with inherent disinfectant properties. This paper aims to critically review recent pre-clinical and clinical advances in using smart hydrogels against skin wound infections and propose the next best thing for future trends. For this purpose, an introduction to skin wound healing and disease is presented and intelligent hydrogels responding to different stimuli are introduced. Finally, the most promising investigations are discussed in their related sections. These studies can pave the way for producing new biomaterials with clinical applications. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | hydrogels | es_ES |
dc.subject | thermo-sensitive | es_ES |
dc.subject | thermo-responsive | es_ES |
dc.subject | wound infections | es_ES |
dc.subject | burn wounds | es_ES |
dc.subject | drug delivery | es_ES |
dc.title | Antibacterial smart hydrogels: New hope for infectious wound management | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S2590006422002976?via%3Dihub | es_ES |
dc.identifier.doi | 10.1016/j.mtbio.2022.100499 | |
dc.departamentoes | Farmacia y ciencias de los alimentos | es_ES |
dc.departamentoeu | Farmazia eta elikagaien zientziak | es_ES |