Palladium-Catalyzed Site-Selective C(sp2)−H Acetoxylation of Tyrosine-Containing Peptides
dc.contributor.author | Urruzuno Guiu, Iñaki | |
dc.contributor.author | Andrade Sampedro, Paula | |
dc.contributor.author | Correa Navarro, Arkaitz ![]() | |
dc.date.accessioned | 2023-03-06T17:33:30Z | |
dc.date.available | 2023-03-06T17:33:30Z | |
dc.date.issued | 2023-02 | |
dc.identifier.citation | European Journal of Organic Chemistry 26(6) : (2023) // Article ID e202201489 | es_ES |
dc.identifier.issn | 1434-193X | |
dc.identifier.issn | 1099-0690 | |
dc.identifier.uri | http://hdl.handle.net/10810/60284 | |
dc.description.abstract | A Pd-catalyzed C(sp2)−H acetoxylation of Tyr-containing peptides is described. The method relies on the use of a removable 2-pyridyloxy group as directing group and is distinguished by its reliable scalability and easily tuned regioselectivity to perform mono- and diacetoxylation reactions. Remarkably, the assembly of L–DOPA peptidomimetics is beyond reach upon cleavage of the directing group. | es_ES |
dc.description.sponsorship | We are grateful to Ministerio de Ciencia e Innovación (RTI2018-093721-B-I00, MCI/AEI/FEDER, UE) and Basque Government (IT-1741-22) for financial support. We thank for the technical and human support provided by Central Service of Analysis-SGIker of UPV/EHU and European funding (ERDF and ESF). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Wiley | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICIU/RTI2018-093721-B-I00 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | acetoxylation | es_ES |
dc.subject | amino acid | es_ES |
dc.subject | C-H functionalization | es_ES |
dc.subject | palladium catalysis | es_ES |
dc.subject | peptides | es_ES |
dc.title | Palladium-Catalyzed Site-Selective C(sp2)−H Acetoxylation of Tyrosine-Containing Peptides | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2022 The Authors. European Journal of Organic Chemistry published by Wiley-VCH GmbH This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. | es_ES |
dc.rights.holder | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.relation.publisherversion | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202201489 | es_ES |
dc.identifier.doi | 10.1002/ejoc.202201489 | |
dc.departamentoes | Química orgánica I | es_ES |
dc.departamentoeu | Kimika organikoa I | es_ES |
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Except where otherwise noted, this item's license is described as © 2022 The Authors. European Journal of Organic Chemistry published by Wiley-VCH GmbH
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.