dc.contributor.author | López Herguedas, Naroa | |
dc.contributor.author | Irazola Duñabeitia, Mireia | |
dc.contributor.author | Álvarez Mora, Iker | |
dc.contributor.author | Orive Arroyo, Gorka | |
dc.contributor.author | Lertxundi Etxebarria, Unax | |
dc.contributor.author | Olivares Zabalandicoechea, Maitane | |
dc.contributor.author | Zuloaga Zubieta, Olatz | |
dc.contributor.author | Prieto Sobrino, Ailette | |
dc.date.accessioned | 2023-06-22T17:42:22Z | |
dc.date.available | 2023-06-22T17:42:22Z | |
dc.date.issued | 2023-05 | |
dc.identifier.citation | Science of The Total Environment 873 : (2023) // Article ID 162281 | es_ES |
dc.identifier.issn | 1879-1026 | |
dc.identifier.issn | 0048-9697 | |
dc.identifier.uri | http://hdl.handle.net/10810/61579 | |
dc.description.abstract | Micropollutants monitoring in wastewater can serve as a picture of what is consuming society and how it can impact the aquatic environment. In this work, a suspect screening approach was used to detect the known and unknown contaminants in wastewater samples collected from two wastewater treatment plants (WWTPs) located in the Basque Country (Crispijana in Alava, and Galindo in Vizcaya) during two weekly sampling campaigns, which included the months from April to July 2020, part of the confinement period caused by COVID-19. To that aim, high-resolution mass spectrometry was used to collect full-scan data-dependent tandem mass spectra from the water samples using a suspect database containing >40,000 chemical substances. The presence of > 80 contaminants was confirmed (level 1) and quantified in both WWTP samples, while at least 47 compounds were tentatively identified (2a). Among the contaminants of concern, an increase in the occurrence of some compounds used for COVID-19 disease treatment, such as lopinavir and hydroxychloroquine, was observed during the lockdown. A prioritization strategy for environmental risk assessment was carried out considering only the compounds quantified in the effluents of Crispijana and Galindo WWTPs. The compounds were scored based on the removal efficiency, estimated persistency, bioconcentration factor, mobility, toxicity potential and frequency of detection in the samples. With this approach, 33 compounds (e.g. amantadine, clozapine or lopinavir) were found to be considered key contaminants in the analyzed samples based on their concentration, occurrence and potential toxicity. Additionally, antimicrobial (RQ-AR) and antiviral (EDRP) risk of certain compounds was evaluated, where ciprofloxacin and fluconazole represented medium risk for antibiotic resistance (1 > RQ-AR > 0.1) in the aquatic ecosystems. Regarding mixture toxicity, the computed sum of toxic unit values of the different effluents (> 1) suggest that interactions between the compounds need to be considered for future environmental risk assessments. | es_ES |
dc.description.sponsorship | This study was funded by the Basque Government through financial support as a consolidated group of the Basque Research System (IT1446-22), the Agencia Estatal de Investigación (AEI) of Spain, the 2020 call for the generation of knowledge and scientific and technological strengthening of the R&D&i system and the R&D&i focused on society's challenges, through project PID2020-117686RB-C31 and the Council of Vitoria-Gasteiz and Fundación Vital. The authors are grateful to the Consorcio de Aguas de Bilbao and especially to Iñigo González. Naroa Lopez-Herguedas is grateful to the Spanish Ministry of Economy, Industry and Competitivity for her predoctoral scholarship FPI 2018. Iker Alvarez-Mora is grateful to the University of the Basque Country and the Université de Pau et des Pays de L' Adour for his cotutelle predoctoral scholarship. Finally, the authors acknowledge support from the AEI and the Ministry of Science, Innovation and Universities (MICIU) to support the Thematic Network of Excellence (NET4SEA) on emerging contaminants in marine settings (CTM2017-90890-REDT, MICIU/AEI/FEDER, EU). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/PID2020-117686RB-C31 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/3.0/es/ | * |
dc.subject | emerging organic contaminants | es_ES |
dc.subject | suspect screening | es_ES |
dc.subject | COVID-19 pandemic | es_ES |
dc.subject | prioritization strategy | es_ES |
dc.subject | WWTP effluent | es_ES |
dc.subject | LC-qOrbitrap | es_ES |
dc.title | Comprehensive micropollutant characterization of wastewater during Covid-19 crisis in 2020: Suspect screening and environmental risk prioritization strategy | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/). | es_ES |
dc.rights.holder | Atribución-NoComercial 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0048969723008975 | es_ES |
dc.identifier.doi | 10.1016/j.scitotenv.2023.162281 | |
dc.departamentoes | Química analítica | es_ES |
dc.departamentoeu | Kimika analitikoa | es_ES |