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dc.contributor.authorNiechi, Ignacio
dc.contributor.authorPineda Martí, José Ramón ORCID
dc.date.accessioned2023-07-05T13:51:23Z
dc.date.available2023-07-05T13:51:23Z
dc.date.issued2023-01-24
dc.identifier.citationFrontiers in Oncology 13 : (2023) // Article ID 1136895es_ES
dc.identifier.issn2234-943X
dc.identifier.urihttp://hdl.handle.net/10810/61889
dc.description.abstractPrimary brain tumors are most commonly detected in the late stages of the disease and there are only a few treatment opportunities. Overall survival rates are significantly low and the response to chemo/radiotherapy is not sufficient, despite surgical intervention. The tumor microenvironment (TME) regulates several brain tumor hallmarks, such as cell migration, invasiveness, proliferation, therapy resistance, stemness maintenance, immune evasion, among others. Therefore, it is necessary to understand the pro-tumoral mechanisms that are regulated by the TME in order to detect and identify new biomarkers and novel therapeutic targets.es_ES
dc.description.sponsorshipIN was supported by ANID/FONDECYT Grant 11220149 and ANID/IMII ICN09-016/ICN 2021-045. JRP was supported by grant PID2019-104766RB-C21 funded by MCIN/AEI/10.13039/501100011033, Basque Government (IT1751-22) and University of the Basque Country (COLAB22/07).es_ES
dc.language.isoenges_ES
dc.publisherFrontierses_ES
dc.relationinfo:eu-repo/grantAgreement/MCIN/PID2019-104766RB-C21es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.titleEditorial: Tumor microenvironment in primary brain cancerses_ES
dc.typeinfo:eu-repo/semantics/otheres_ES
dc.rights.holder© 2023 Niechi and Pineda. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.es_ES
dc.relation.publisherversionhttps://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1136895es_ES
dc.identifier.doi10.3389/fonc.2023.1136895
dc.departamentoesBiología celular e histologíaes_ES
dc.departamentoeuZelulen biologia eta histologiaes_ES


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© 2023 Niechi and Pineda. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Except where otherwise noted, this item's license is described as © 2023 Niechi and Pineda. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.