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dc.contributor.authorVallejo, Pedro
dc.contributor.authorCilla Eguiluz, Carlos Gustavo
dc.contributor.authorLópez Olaizola, Maddi
dc.contributor.authorVicente Anza, Diego
dc.contributor.authorMarimón Ortiz de Zarate, José María
dc.date.accessioned2023-07-05T17:23:20Z
dc.date.available2023-07-05T17:23:20Z
dc.date.issued2022-06
dc.identifier.citationFrontiers in Microbiology 13 : (2022) // Article ID 894334es_ES
dc.identifier.issn1664-302X
dc.identifier.urihttp://hdl.handle.net/10810/61900
dc.description.abstractBackground: Listeriosis continues to be one of the most important notifiable foodborne diseases. Nonetheless, in Spain, there are few data on the molecular epidemiology of Listeria monocytogenes infections in recent years. Aim: To describe clinical features and the molecular epidemiology of human listeriosis over an 11-year period (2010–2020) in Gipuzkoa, Northern Spain. Methods: A total of 111 isolates, all but one from invasive disease, were studied. Serotyping (agglutination and multiplex polymerase chain reaction [PCR]) and multilocus sequence typing were performed for all isolates. Antibiotic susceptibility was assessed by the broth microdilution method. Results: The average annual incidence of listeriosis in non-pregnancy-associated cases was 1.55 per 100,000 population, with a 1-month mortality rate of 22.2%. In pregnant women, the average incidence was 0.45 cases per 1,000 pregnancies. Twenty-four sequence types were identified, serotype 4b ST1 (24.3%) being the most frequent followed by 1/2b ST87 (18.9%), which caused two long outbreaks in 2013–2014. A significant association was observed between ST219 and meningitis (p < 0.001). All isolates were susceptible to ampicillin as well as other antibiotics used in listeriosis treatment. Conclusion: Despite current control measures, listeriosis continues to be an important cause of mortality in the elderly, preterm birth, and miscarriages in pregnant women. Improvements in the control and diagnosis of listeriosis are needed to reduce the impact of this infection on vulnerable populations.es_ES
dc.language.isoenges_ES
dc.publisherFrontiers Mediaes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectListeria monocytogeneses_ES
dc.subjectlisteriosises_ES
dc.subjectzoonosises_ES
dc.subjectfood - borne pathogenses_ES
dc.subjectMLST (multilocus sequence typing)es_ES
dc.titleEpidemiology and Clinical Features of Listeriosis in Gipuzkoa, Spain, 2010–2020es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holder© 2022 Vallejo, Cilla, López-Olaizola, Vicente and Marimón. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.es_ES
dc.rights.holderAtribución 3.0 España*
dc.relation.publisherversionhttps://www.frontiersin.org/articles/10.3389/fmicb.2022.894334/fulles_ES
dc.identifier.doi10.3389/fmicb.2022.894334
dc.departamentoesMedicina preventiva y salud públicaes_ES
dc.departamentoeuPrebentzio medikuntza eta osasun publikoaes_ES


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© 2022 Vallejo, Cilla, López-Olaizola, Vicente and Marimón. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Except where otherwise noted, this item's license is described as © 2022 Vallejo, Cilla, López-Olaizola, Vicente and Marimón. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.