Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments
dc.contributor.author | García Etxebarria, Koldo | |
dc.contributor.author | Etxart, Ane | |
dc.contributor.author | Barrero, Maialen | |
dc.contributor.author | Nafria, Beatriz | |
dc.contributor.author | Segues Merino, Nerea Miren | |
dc.contributor.author | Romero Garmendia, Irati | |
dc.contributor.author | Goel, Ajay | |
dc.contributor.author | Franke, Andre | |
dc.contributor.author | D’Amato, Mauro | |
dc.contributor.author | Bujanda Fernández de Pierola, Luis | |
dc.date.accessioned | 2023-10-16T16:53:30Z | |
dc.date.available | 2023-10-16T16:53:30Z | |
dc.date.issued | 2023-09-22 | |
dc.identifier.citation | Cancers 15(19) : (2023) // Article ID 4688 | es_ES |
dc.identifier.issn | 2072-6694 | |
dc.identifier.uri | http://hdl.handle.net/10810/62848 | |
dc.description.abstract | Some colorectal cancer (CRC) outcomes are partially associated with genetics, and different studies have proposed several genetic variants as predictors. However, analysis of their performance in other populations is limited. Thus, our objectives were to assess their use in our cohort and to find additional genetic variants associated with CRC outcomes. We found that some of the genetic variants proposed as predictors could be used in our cohort, although the addition of clinical data improved the performance. In addition, we found additional genetic variants that could be useful to predict the CRC manifestations in our population. Our findings will help to refine the use of genetic polymorphisms to predict CRC outcomes in our population, and we expect that our findings could be useful for other populations. | es_ES |
dc.description.sponsorship | This work was partially founded by Gipuzkoako Foru Aldundia/Diputación Foral de Gipuzkoa (Code: 111/17) | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | colorectal cancer | es_ES |
dc.subject | outcomes | es_ES |
dc.subject | genetics | es_ES |
dc.subject | markers | es_ES |
dc.subject | survival | es_ES |
dc.subject | treatment | es_ES |
dc.subject | genetic association | es_ES |
dc.title | Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2023-10-13T12:07:42Z | |
dc.rights.holder | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/2072-6694/15/19/4688 | es_ES |
dc.identifier.doi | 10.3390/cancers15194688 | |
dc.departamentoes | Medicina | |
dc.departamentoeu | Medikuntza |
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Except where otherwise noted, this item's license is described as © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).