dc.contributor.author | Carral Menoyo, Asier | |
dc.contributor.author | Sotomayor Anduiza, María Nuria | |
dc.contributor.author | Lete Expósito, María Esther | |
dc.date.accessioned | 2023-11-24T11:59:22Z | |
dc.date.available | 2023-11-24T11:59:22Z | |
dc.date.issued | 2020-05-18 | |
dc.identifier.citation | Catalysis Science & Technology 10 : 5345-5361(2020) | es_ES |
dc.identifier.issn | 2044-4753 | |
dc.identifier.issn | 2044-4761 | |
dc.identifier.uri | http://hdl.handle.net/10810/63145 | |
dc.description.abstract | Quinoline and quinolone cores are present in a wide variety of pharmaceuticals, agrochemicals and materials, as well in ligands/catalysts in asymmetric synthesis. Transition-metal catalysed based approaches have played a pivotal role in the development of the catalytic methods for their synthesis. This review presents recent developments on palladiumcatalysed Mizoroki-Heck reaction and its dehydrogenative variant (the Fujiwara-Moritani reaction), a C-H activation reaction that does not require the use of prefunctionalized coupling parterns for the synthesis of quinoline frameworks. The mechanistic understanding of both type of reactions, and how the different reaction conditions affect the outcome and the regioselectivity for the synthesis of the quinoline core, which is crucial to achieve target-oriented synthesis successfully, is discussed through selected examples. | es_ES |
dc.description.sponsorship | Ministerio de Economía y Competitividad (CTQ2016-74881-P) // Gobierno Vasco (IT1045-16) | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Royal Society of Chemistry | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/CTQ2016-74881-P | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | palladium | es_ES |
dc.subject | C-H activation | es_ES |
dc.subject | Heck reaction | es_ES |
dc.subject | quinolines | es_ES |
dc.title | Palladium-catalysed Heck-type alkenylation reactions in the synthesis of quinolines. Mechanistic insights and recent applications | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2020, The Royal Society of Chemistry | es_ES |
dc.relation.publisherversion | https://pubs.rsc.org/en/content/articlelanding/2020/cy/d0cy00789g | es_ES |
dc.relation.publisherversion | https://doi.org/10.1039/D0CY00789G | es_ES |
dc.identifier.doi | 10.1039/D0CY00789G | |
dc.departamentoes | Química Orgánica e Inorgánica | es_ES |
dc.departamentoeu | Kimika Organikoa eta Ez-Organikoa | es_ES |