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Liquid-Core Microstructured Polymer Optical Fiber as Fiber-Enhanced Raman Spectroscopy Probe for Glucose Sensing

dc.contributor.authorAzkune Ulla, Mikel ORCID
dc.contributor.authorFrosch, Timea
dc.contributor.authorArrospide Zabala, Eneko ORCID
dc.contributor.authorAldabaldetreku Etxeberria, Gotzon
dc.contributor.authorBikandi Irazabal, Iñaki ORCID
dc.contributor.authorZubia Zaballa, Joseba Andoni
dc.contributor.authorPopp, Jurgen
dc.contributor.authorFrosch, Torsten
dc.date.accessioned2024-02-06T15:34:11Z
dc.date.available2024-02-06T15:34:11Z
dc.date.issued2019-07
dc.identifier.citationJournal of Lightwave Technology 37(13) : 2981-2988 (2019)es_ES
dc.identifier.issn0733-8724
dc.identifier.urihttp://hdl.handle.net/10810/64683
dc.description.abstract[EN] This work reports the development and application of two liquid-core microstructured polymer optical fibers (LCmPOF) with different microstructure sizes. They are used in a fiber-enhanced Raman spectroscopy sensing platform,with the aim of detecting glucose in aqueous solutions in the clinically relevant range for sodium–glucose cotransporter 2 inhibitor therapy. The sensing platform is tested for low-concentration glucose solutions using each LC-mPOF. Results confirm that a significant enhancement of theRaman signal is achieved in comparison to conventional Raman spectroscopy. Additional measurements are carried out to obtain the valid measurement range, the resolution, and the limit of detection, showing that the LC-mPOF with 66-μm-diameter central hollow core has the highest potential for future clinical applications. Finally, preliminary tests successfully demonstrate glucose identification in urine.es_ES
dc.description.sponsorshipThis work was supported in part by European Regional Development Fund, in part by the Ministerio de Economía y Competitividad under Project TEC2015-638263-C03-1-R, in part by Gobierno Vasco/Eusko Jaurlaritza under Projects IT933-16 and ELKARTEK (KK-2016/0030, KK-2017/00033, KK- 2017/00089, and KK-2016/0059), and in part by the Free State of Thuringia, Germany (2015 FE 9012). The work of M. Azkune was supported in part by a research fellowship from the University of the Basque Country, Vicerrectorado de Euskera y Formación Continua. (Corresponding author: Mikel Azkune.)es_ES
dc.language.isoenges_ES
dc.publisherIEEEes_ES
dc.relationinfo:eu-repo/grantAgreement/MINECO/TEC2015-638263-C03-1-Res_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/*
dc.subjectfiber enhanced Raman spectroscopyes_ES
dc.subjectglucose sensinges_ES
dc.subjecthollow-core microstructured polymer optical fiberses_ES
dc.titleLiquid-Core Microstructured Polymer Optical Fiber as Fiber-Enhanced Raman Spectroscopy Probe for Glucose Sensinges_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holderThis work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0es_ES
dc.relation.publisherversionhttps://ieeexplore.ieee.org/document/8678391es_ES
dc.identifier.doi10.1109/JLT.2019.2908447
dc.departamentoesIngeniería de comunicacioneses_ES
dc.departamentoeuKomunikazioen ingeniaritzaes_ES


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This work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0
Except where otherwise noted, this item's license is described as This work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0