dc.contributor.author | Campano García, Teresa Esperanza | |
dc.contributor.author | Iriarte Arrieta, Igor | |
dc.contributor.author | Olaizola Aizpuru, Olatz | |
dc.contributor.author | Etxabe Tellería, Julen | |
dc.contributor.author | Mielgo Vicente, María Antonia ![ORCID](/themes/Mirage2//images/orcid_16x16.png) | |
dc.contributor.author | Gamboa Landa, José Ignacio | |
dc.contributor.author | Odriozola, José M. | |
dc.contributor.author | García, Jesús María | |
dc.contributor.author | Oyarbide Garmendia, Juan Miguel ![ORCID](/themes/Mirage2//images/orcid_16x16.png) | |
dc.contributor.author | Palomo Nicolau, Claudio | |
dc.date.accessioned | 2024-02-08T09:57:12Z | |
dc.date.available | 2024-02-08T09:57:12Z | |
dc.date.issued | 2019-03-21 | |
dc.identifier.citation | Chemistry 25(17) : 4390-4397 (2019) | |
dc.identifier.issn | 0947-6539 | |
dc.identifier.uri | http://hdl.handle.net/10810/65179 | |
dc.description.abstract | Various sets of enolizable alkynyl ketones (including methyl ynones with α-aryl, α-alkenyl, and α-alkoxy groups) were able to react smoothly with nitroolefins with the assistance of bifunctional Brønsted base/H-bond catalysts to provide adducts with two consecutive tertiary stereocenters in a highly diastereo- and enantioselective fashion. Further transformation of the obtained adducts into optically active acyclic and polycyclic molecules, including some with intricate carbon skeletons, was also demonstrated. | |
dc.description.sponsorship | Financial support was provided by the University of the Basque Country UPV/EHU (UFI QOSYC 11/22), Basque Government (BG Grant No IT-628-13), and Ministerio de Economía y Competitividad (MINECO, Grant CTQ2016-78487-C2), Spain, T.C. thanks MINECO, and I.I. and O.O. thank BG for fellowships. We also thank SGiker (UPV/EHU) for providing NMR, HRMS, and X-ray resources. | |
dc.language.iso | eng | es_ES |
dc.publisher | Wiley | |
dc.relation | info:eu-repo/grantAgreement/MINECO/CTQ2016-78487-C2 | |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | alkynyl ketones | |
dc.subject | asymmetric catalysis | |
dc.subject | Brønsted bases | |
dc.subject | Michael reaction | |
dc.subject | organocatalysis | |
dc.title | Enantioselective Addition of Alkynyl Ketones to Nitroolefins Assisted by Bronsted Base/H-Bonding Catalysis | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim | * |
dc.relation.publisherversion | https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.201805542 | |
dc.identifier.doi | 10.1002/chem.201805542 | |
dc.departamentoes | Química orgánica I | es_ES |
dc.departamentoeu | Kimika organikoa I | es_ES |
dc.identifier.eissn | 1521-3765 | |