dc.contributor.author | Eufrásio da Silva, Tatiane | |
dc.contributor.author | Erezuma Aldamiz-Etxebarria, Itsasne | |
dc.contributor.author | Dolatshahi-Pirouz, Alireza ![ORCID](/themes/Mirage2//images/orcid_16x16.png) | |
dc.contributor.author | Orive Arroyo, Gorka | |
dc.date.accessioned | 2024-05-15T16:11:42Z | |
dc.date.available | 2024-05-15T16:11:42Z | |
dc.date.issued | 2024-07 | |
dc.identifier.citation | Biomaterials Advances 161 : (2024) // Article ID 213869 | es_ES |
dc.identifier.issn | 2772-9508 | |
dc.identifier.uri | http://hdl.handle.net/10810/67969 | |
dc.description.abstract | Considering the global burden related to tissue and organ injuries or failures, self-healing hydrogels may be an attractive therapeutic alternative for the future. Self-healing hydrogels are highly hydrated 3D structures with the ability to self-heal after breaking, this property is attributable to a variety of dynamic non-covalent and covalent bonds that are able to re-linking within the matrix. Self-healing ability specially benefits minimal invasive medical treatments with cell-delivery support. Moreover, those tissue-engineered self-healing hydrogels network have demonstrated effectiveness for myriad purposes; for instance, they could act as delivery-platforms for different cargos (drugs, growth factors, cells, among others) in tissues such as bone, cartilage, nerve or skin. Besides, self-healing hydrogels have currently found their way into new and novel applications; for example, with the development of the self-healing adhesive hydrogels, by merely aiding surgical closing processes and by providing biomaterial-tissue adhesion. Furthermore, conductive hydrogels permit the stimuli and monitoring of natural electrical signals, which facilitated a better fitting of hydrogels in native tissue or the diagnosis of various health diseases. Lastly, self-healing hydrogels could be part of cyborganics – a merge between biology and machinery – which can pave the way to a finer healthcare devices for diagnostics and precision therapies. | es_ES |
dc.description.sponsorship | We would like to express our appreciation appreciate for the financial support from the Spanish Ministry of Economy, Industry, and Competitiveness (PID2022-139746OB-I00/AEI/10.13039/501100011033) at the University of the Basque Country. Itsasne Erezuma thanks the Basque Government for the Ph.D. grant. Alireza Dolatshahi-Pirouz would also like to acknowledge the Danish Council for Independent Research (Technology and Production Sciences, 8105–00003B), and the VIDI research programme (Project number R0004387), which is (partly) financed by The Netherlands Organisation for Scientific Research (NWO); moreover, as this work has also received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 951747, as well as from Novo Nordisk Foundation under grant agreement No NNF22OC007994. Besides, we would like to thank BioRender.com for the graphic design that we prepared for this work. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/951747 | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/PID2022-139746OB-I00 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.title | Enhancing regenerative medicine with self-healing hydrogels: A solution for tissue repair and advanced cyborganic healthcare devices | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2024 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S277295082400112 | es_ES |
dc.identifier.doi | 10.1016/j.bioadv.2024.213869 | |
dc.contributor.funder | European Commission | |
dc.departamentoes | Farmacia y ciencias de los alimentos | es_ES |
dc.departamentoeu | Farmazia eta elikagaien zientziak | es_ES |