dc.contributor.author | Gutiérrez Ruiz, José Julio ![ORCID](/themes/Mirage2//images/orcid_16x16.png) | |
dc.contributor.author | Sandoval, Camilo Leonardo | |
dc.contributor.author | Leturiondo Sota, Mikel ![ORCID](/themes/Mirage2//images/orcid_16x16.png) | |
dc.contributor.author | Russell, James Knox | |
dc.contributor.author | Redondo Serrano, Koldo | |
dc.contributor.author | Daya, Mohamud Ramzan | |
dc.contributor.author | Ruiz de Gauna Gutiérrez, Sofía ![ORCID](/themes/Mirage2//images/orcid_16x16.png) | |
dc.date.accessioned | 2024-05-28T15:47:11Z | |
dc.date.available | 2024-05-28T15:47:11Z | |
dc.date.issued | 2022-10 | |
dc.identifier.citation | Resuscitation 179 : 225-232 (2022) | es_ES |
dc.identifier.issn | 0300-9572 | |
dc.identifier.issn | 1873-1570 | |
dc.identifier.uri | http://hdl.handle.net/10810/68236 | |
dc.description.abstract | Aim
Characterise how changes in chest compression depth and rate affect variations in end-tidal CO2 (ETCO2) during manual cardiopulmonary resuscitation (CPR) in out-of-hospital cardiac arrest (OHCA).
Methods
Retrospective analysis of adult OHCA monitor-defibrillator recordings having concurrent capnogram, compression depth, transthoracic impedance and ECG, and with atleast 1,000 compressions. Within each patient, during no spontaneous circulation, nearby segments with changes in chest compression depth and rate were identified. Average ETCO2 within each segment was standardised to compensate for ventilation rate variability. Contributions of relative variations in depth and rate to relative variations in standardised ETCO2 were characterised using linear and non-linear models. Normalisation between paired segments removed intra and inter-patient variation and made coefficients of the model independent of the scale of measurement and therefore directly comparable.
Results
A total of 394 pairs of segments from 221 patients were analysed (33% female, median (IQR) age 66 (55–74) years). Chest compression depth and rate were 50.4 (43.2–57.0) mm and 111.1 (106.5–116.1) compressions per minute. ETCO2 before and after standardization was 32.1 (23.0–41.4) mmHg and 28.5 (19.4–38.7) mmHg. Linear model coefficient of determination was 0.89. Variation in compression depth mainly explained ETCO2 variation (coefficient 0.95, 95% confidence interval (CI): 0.93–0.98) while changes in compression rate did not (coefficient 0.04, 95% CI: 0.01–0.07). Non-linear trend analysis confirmed the results.
Conclusion
This study quantified the relative importance of chest compression characteristics in terms of their impact on CO2 production during CPR. With ventilation rate standardised, variation in chest compression depth explained variations in ETCO2 better than variation in chest compression rate | es_ES |
dc.description.sponsorship | This study was funded by the grant RTI2018-094396-B-I00 by MCIN/AEI/10.13039/501100011033 and by ERDF A way of making Europe. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICIU/RTI2018-094396-B-I00 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | cardiopulmonary resuscitation (CPR) | es_ES |
dc.subject | chest compression quality | es_ES |
dc.subject | chest compression depth | es_ES |
dc.subject | chest compression rate | es_ES |
dc.subject | ventilation rate | es_ES |
dc.subject | end-tidal CO2 | es_ES |
dc.subject | out-of-hospital cardiac arrest (OHCA) | es_ES |
dc.subject | advanced life support (ALS) | es_ES |
dc.title | Contribution of chest compressions to end-tidal carbon dioxide levels generated during out-of-hospital cardiopulmonary resuscitation | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | es_ES |
dc.rights.holder | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0300957222005998 | es_ES |
dc.identifier.doi | 10.1016/j.resuscitation.2022.07.009 | |
dc.departamentoes | Ingeniería de comunicaciones | es_ES |
dc.departamentoes | Tecnología electrónica | es_ES |
dc.departamentoeu | Komunikazioen ingeniaritza | es_ES |
dc.departamentoeu | Teknologia elektronikoa | es_ES |