dc.contributor.author | Gutiérrez Ruiz, José Julio | |
dc.contributor.author | Urigüen Garaizabal, José Antonio | |
dc.contributor.author | Leturiondo Sota, Mikel | |
dc.contributor.author | Sandoval, Camilo Leonardo | |
dc.contributor.author | Redondo Serrano, Koldo | |
dc.contributor.author | Russell, James Knox | |
dc.contributor.author | Daya, Mohamud Ramzan | |
dc.contributor.author | Ruiz de Gauna Gutiérrez, Sofía | |
dc.date.accessioned | 2024-08-05T11:50:16Z | |
dc.date.available | 2024-08-05T11:50:16Z | |
dc.date.issued | 2024-07 | |
dc.identifier.citation | Resuscitation 200 : (2024) // Article ID 110259 | es_ES |
dc.identifier.issn | 0300-9572 | |
dc.identifier.issn | 1873-1570 | |
dc.identifier.uri | http://hdl.handle.net/10810/69143 | |
dc.description.abstract | Background
Interpretation of end-tidal CO2 (ETCO2) during manual cardiopulmonary resuscitation (CPR) is affected by variations in ventilation and chest compressions. This study investigates the impact of standardising ETCO2 to constant ventilation rate (VR) and compression depth (CD) on absolute values and trends.
Methods
Retrospective study of out-of-hospital cardiac arrest cases with manual CPR, including defibrillator and clinical data. ETCO2, VR and CD values were averaged by minute. ETCO2 was standardised to 10 vpm and 50 mm. We compared standardised (ETs) and measured (ETm) values and trends during resuscitation.
Results
Of 1,036 cases, 287 met the inclusion criteria. VR was mostly lower than recommended, 8.8 vpm, and highly variable within and among patients. CD was mostly within guidelines, 49.8 mm, and less varied. ETs was lower than ETm by 7.3 mmHg. ETs emphasized differences by sex (22.4 females vs. 25.6 mmHg males), initial rhythm (29.1 shockable vs. 22.7 mmHg not), intubation type (25.6 supraglottic vs. 22.4 mmHg endotracheal) and return of spontaneous circulation (ROSC) achieved (34.5 mmHg) vs. not (20.1 mmHg). Trends were different between non-ROSC and ROSC patients before ROSC (–0.3 vs. + 0.2 mmHg/min), and between sustained and rearrest after ROSC (–0.7 vs. –2.1 mmHg/min). Peak ETs was higher for sustained than for rearrest (53.0 vs. 42.5 mmHg).
Conclusion
Standardising ETCO2 eliminates effects of VR and CD variations during manual CPR and facilitates comparison of values and trends among and within patients. Its clinical application for guidance of resuscitation warrants further investigation. | es_ES |
dc.description.sponsorship | The grant PID2021-126021OB-I00 by MICIU/AEI/10.13039/501100011033 and by ERDF/UE, and the grant IT1590-22 by the Basque Government financially supported this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/PID2021-126021OB-I00 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | CPR | es_ES |
dc.subject | ETCO2 | es_ES |
dc.subject | ventilation rate | es_ES |
dc.subject | compression depth | es_ES |
dc.subject | capnography | es_ES |
dc.subject | ROSC | es_ES |
dc.subject | prognosis | es_ES |
dc.title | Standardisation facilitates reliable interpretation of ETCO2 during manual cardiopulmonary resuscitation | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2024 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | es_ES |
dc.rights.holder | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0300957224001527 | es_ES |
dc.identifier.doi | 10.1016/j.resuscitation.2024.110259 | |
dc.departamentoes | Ingeniería de comunicaciones | es_ES |
dc.departamentoes | Matemática aplicada | es_ES |
dc.departamentoeu | Komunikazioen ingeniaritza | es_ES |
dc.departamentoeu | Matematika aplikatua | es_ES |