dc.contributor.author | Ortega, Alesandere | |
dc.contributor.author | Uria Pujana, Uxue | |
dc.contributor.author | Tejero, Tomás | |
dc.contributor.author | Prieto Aretxabaleta, Liher | |
dc.contributor.author | Reyes Martín, Efraim | |
dc.contributor.author | Merino, Pedro | |
dc.contributor.author | Vicario Hernando, José Luis | |
dc.date.accessioned | 2024-10-15T16:02:22Z | |
dc.date.available | 2024-10-15T16:02:22Z | |
dc.date.issued | 2021-03 | |
dc.identifier.citation | Organic Letters 23(6) : 2326-2331 (2021) | es_ES |
dc.identifier.issn | 1523-7060 | |
dc.identifier.issn | 1523-7052 | |
dc.identifier.uri | http://hdl.handle.net/10810/69960 | |
dc.description.abstract | Acylcyclopropanes are employed as useful donor−acceptor cyclopropanes that undergo formal (4 + 2) cyclo-condensation with N-unprotected 3-substituted indoles in thepresence of a Brønsted acid catalyst. The reaction involves thesimultaneous alkylation of both the N and C-2 positions of theindole and provides access to the 8,9-dihydropyrido[1,2-a]indolescaffold that is the central core of several biologically relevantindole alkaloids in excellent yields and good selectivities | es_ES |
dc.description.sponsorship | Spanish MINECO(PID2019-104090RB-100 and FEDER-CTQ2016-76155-R), Basque Government (IT908-16), UPV/EHU (fellowship to A.O.), and Government of Aragón (Grupos Consolidados,E34_20R). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | ACS Publications | es_ES |
dc.relation | info:eu-repo/grantAgreement/MICINN/PID2019-104090RB-100 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | donor−acceptor cyclopropanes | es_ES |
dc.subject | acylcyclopropanes | es_ES |
dc.subject | (4 + 2) cyclocondensation | es_ES |
dc.subject | brønsted acid catalyzed | es_ES |
dc.title | Brønsted Acid Catalyzed (4 + 2) Cyclocondensation of 3-Substituted Indoles with Donor–Acceptor Cyclopropanes | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2021 American Chemical Society . This publication is licensed under CC-BY 4.0 | es_ES |
dc.relation.publisherversion | https://pubs.acs.org/doi/10.1021/acs.orglett.1c00470 | es_ES |
dc.identifier.doi | 10.1021/acs.orglett.1c00470 | |
dc.departamentoes | Química Orgánica e Inorgánica | es_ES |
dc.departamentoeu | Kimika Organikoa eta Ez-Organikoa | es_ES |