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Extracellular Vesicles in Hepatobiliary Malignancies
(Frontiers Media, 2018-10-12)
Primary hepatobiliary malignancies include a heterogeneous group of cancers with dismal prognosis, among which hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), and hepatoblastoma (HB) stand out. These tumors mainly ...
Advances in Single-Chain Nanoparticles for Catalysis Applications
(MDPI, 2017-10-21)
Enzymes are the most efficient catalysts known for working in an aqueous environment near room temperature. The folding of individual polymer chains to functional single-chain nanoparticles (SCNPs) offers many opportunities ...
Risk management for mathematical optimization under uncertainty
(2016)
We present a general multistage stochastic mixed 0-1 problem where the uncertainty appears everywhere in the objective function, constraints matrix and right-hand-side. The uncertainty is represented by a scenario tree ...
Efficient Synthesis of Single-Chain Polymer Nanoparticles via Amide Formation
(Hindawi Publishing, 2015)
Single-chain technology (SCT) allows the transformation of individual polymer chains to folded/collapsed unimolecular soft nanoparticles. In this work we contribute to the enlargement of the SCT toolbox by demonstrating ...
Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma
(Public Library Science, 2014-04-17)
Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...
J48Consolidated: an implementation of CTC algorithm for WEKA
(2016-02-12)
The CTC algorithm, Consolidated Tree Construction algorithm, is a machine learning paradigm that was designed to solve a class imbalance problem, a fraud detection problem in the area of car insurance [1] where, besides, ...
Electronic and spintronic devices using two-dimensional materials
(2017-05-30)
Ever since in 2004 atomically-thin two-dimensional van der Waals materials became available to the scientific community, at the reach of manual microexfoliation techniques, their implementation in novel device structures ...
Ibero-American Consensus on Low- and No-Calorie Sweeteners: Safety, Nutritional Aspects and Benefits in Food and Beverages
(MDPI, 2018-06-25)
International scientific experts in food, nutrition, dietetics, endocrinology, physical activity, paediatrics, nursing, toxicology and public health met in Lisbon on 2-4 July 2017 to develop a Consensus on the use of low- ...
Weighted lambda superstrings applied to vaccine design
(Public Library Science, 2019-02-08)
We generalize the notion of lambda-superstrings, presented in a previous paper, to the notion of weighted lambda-superstrings. This generalization entails an important improvement in the applications to vaccine designs, ...
Flexural Strength Prediction Models for Soil–Cement from Unconfined Compressive Strength at Seven Days
(MDPI, 2019-01-26)
Soil⁻cement is an environmentally friendly road construction technique for base and subbase materials, which allows employing soils placed in the right-of-way of the road or in the surroundings, by improving its engineering ...