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Now showing items 11-19 of 19
Influence Of Oxygen Partial Pressure On The Characteristics Of Human Hepatocarcinoma Cells
(Elsevier Science BV, 2017-08)
Most of the in vitro studies using liver cell lines have been performed under atmospheric oxygen partial pressure (21% O-2). However, the oxygen concentrations in the liver and cancer cells are far from this value. In the ...
Effectiveness of a multicomponent exercise program in the attenuation of frailty in long-term nursing home residents: study protocol for a randomized clinical controlled trial
(Biomed Central, 2017-02-23)
Background: There is increasing evidence suggesting that cognition and physical frailty interact within a cycle of decline associated with aging which has been called cognitive frailty. Exercise programs have demonstrated ...
Health-related quality of life, handgrip strength and falls during detraining in elderly habitual exercisers
(Biomed Central, 2017-11-21)
Background: The effects of regular exercise on physical functioning and health-related quality of life (HRQOL) have been thoroughly studied. In contrast, little is known about the changes which occur following cessation ...
Lifestyle Patterns and Weight Status in Spanish Adults: The ANIBES Study
(MDPI, 2017-06)
Limited knowledge is available on lifestyle patterns in Spanish adults. We investigated dietary patterns and possible meaningful clustering of physical activity, sedentary behavior, sleep time, and smoking in Spanish adults ...
Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts
(Biomed Central, 2017-04-27)
Background: The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on ...
Targeting mitochondria and post-traslational modifications: new promising approaches for the treatment of liver disease
(2017-04-24)
En esta tesis doctoral hemos corroborado que tanto una correcta función mitocondrial como la homeostasis de proteínas son fundamentales para el correcto funcionamiento del hígado y que alteraciones en ambos procesos están ...
Post-translational modifications in liver disease
(2017-04-07)
La enfermedad hepática crónica es un término que incluye una larga lista de patologías hepáticas y que suele finalizar con la pérdida de integridad del parénquima hepático degenerando en cirrosis y carcinoma hepatocelular ...
Quantitative analyses in basic, translational and clinical biomedical research: metabolism, vaccine design and preterm delivery prediction
(2017-09-11)
There is nothing more important than preserving life, and the thesis here presented is framed in the field of quantitative biomedicine (or systems biomedicine), which has as objective the application of physico-mathematical ...
SREBP-2-driven transcriptional activation of human SND1 oncogene
(Impact Journals LLC, 2017-12-08)
Upregulation of Staphylococcal nuclease and tudor domain containing 1 (SND1) is linked to cancer progression and metastatic spread. Increasing evidence indicates that SND1 plays a role in lipid homeostasis. Recently, it ...