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Caracterización celular y funcional del receptor para colágeno DDR1 en la respuesta del microambiente hepático al cáncer de colón metastásico
(2020-07-15)
El receptor para colágeno DDR1 está implicado en la progresión y la metástasis de multitud de tipos de cáncer, incluido el carcinoma colorrectal. En la mayoría de los casos, las células tumorales de colon metastatizan en ...
Contributions of Women in Recent Research on Biopolymer Science
(MDPI, 2022-03-30)
Nowadays, biopolymers are playing a fundamental role in our society because of the environmental issues and concerns associated with synthetic polymers. The aim of this Special Issue entitled ‘Women in Polymer Science and ...
Chronology protection implementation in analogue gravity
(Springer, 2022)
[EN] Analogue gravity systems offer many insights into gravitational phenomena, both at the classical and at the semiclassical level. The existence of an underlying Minkowskian structure (or Galilean in the non-relativistic ...
Role of Furin in Colon Cancer Stem Cells Malignant Phenotype and Expression of LGR5 and NANOG in KRAS and BRAF-Mutated Colon Tumors
(MDPI, 2022-02-25)
Proprotein convertases or PCs are known to regulate the malignant phenotype of colon cancer cells by different mechanisms, but their effects on cancer stem cells (CSCs) have been less widely investigated. Here, we report ...
Cannabinoid-mediated Modulation of Oxidative Stress and Early Inflammatory Response after Hypoxia–Ischemia
(MDPI, 2020-02-14)
In the process of neonatal encephalopathy, oxidative stress and neuroinflammation have a prominent role after perinatal asphyxia. With the exception of therapeutic hypothermia, no therapeutic interventions are available ...
Cytocompatibility and Suitability of Protein-Based Biomaterials as Potential Candidates for Corneal Tissue Engineering
(MDPI, 2021-03-31)
The vision impairments suffered by millions of people worldwide and the shortage of corneal donors show the need of substitutes that mimic native tissue to promote cell growth and subsequent tissue regeneration. The current ...
Zona Pellucida sperm-binding protein 3 receptor distribution during Gopc−/− globozoospermic spermatogenesis
(Wiley, 2022-04)
[EN] Globozoospermia is a type of teratozoospermia characterized by round morphology of the sperm head. Gopc(-/-) infertile globozoospermic murine model has failures during spermiogenesis, such as the incorrect biogenesis ...
Role of VEGFC C-terminal fragment in colorectal cancer with metastatic capacity.
(2022-05-04)
En el siglo XXI, el cáncer se ha convertido en la segunda causa de muerte en todo el mundo. Esta enfermedad es el resultado de un conjunto de mutaciones, provocando que las células crezcan, se dividan y se propaguen sin ...
The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer
(MDPI, 2022-09-20)
The endocannabinoid system is widespread through the body and carries out a wide variety of functions. However, its involvement in other pathologies, such as cancer, still needs further attention. We aim to investigate the ...
Altered expression of fibroblast activation protein-α (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases
(Impact Journals, 2020-06-15)
Colorectal cancer (CRC) is a major health problem in elderly people because of its high incidence and high mortality rate. Despite early screening programs, more than half of CRC patients are diagnosed at advanced stages. ...