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Caracterización de las células de Schwann cutáneas: análisis de su origen embrionario e implicación en el desarrollo de neurofibromas dérmicos
(2018-07-18)
En la piel, y posiblemente en otros tejidos, la identificación de poblaciones celulares -stem- bajo un excesivo número de denominaciones ha generado confusión en el campo, debido a la reformulación constante de la nomenclatura ...
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
(BioMed Central, 2011-08)
Background: Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanisms ...
Insuficiencia Renal en el Mieloma Múltiple. Análisis de factores pronósticos. Estudio de una serie de 307 pacientes tratados en un Servicio de Medicina Interna
(2017-09-28)
La insuficiencia renal al debut en el Mieloma Multiple sucede entre 20-25% de los casos; y es un factor de mal pronóstico conocido. Hemos realizado un estudio retrospectivo de una cohorte histórica de 307 pacientes, ...
Perinatal hipoxic ischemic injury in the auditory pathway and the effect of several neuroprotective agents
(2015-10-16)
Despite improvements in neonatology, perinatal hypoxic-ischemic (HI) encephalopathy remains one of the main causes of disabilities in term-born infants. This specific pathology underlies many neurological disorders such ...
Dexamethasone Protects Retinal Ganglion Cells But Not Muller Glia Against Hyperglycemia In Vitro
(Public Library Science, 2018-11-26)
Diabetic retinopathy (DR) is a common complication of diabetes, for which hyperglycemia is a major etiological factor. It is known that retinal glia (Muller cells) and retinal ganglion cells (RGCs) are affected by diabetes, ...
Effect of Hypoxia on the Retina and Superior Colliculus of Neonatal Pigs
(Public LIbrary Science, 2017-04-13)
Purpose
To evaluate the effect of hypoxia on the neonatal pig retina and brain, we analysed the retinal ganglion cells (RGCs) and neurons in the superior colliculus, as well as the response of astrocytes in both these ...
Effect of Neonatal Asphyxia on the Impairment of the Auditory Pathway by Recording Auditory Brainstem Responses in Newborn Piglets: A New Experimentation Model to Study the Perinatal Hypoxic-Ischemic Damage on the Auditory Syste
(Public Library Science, 2015-05-26)
Introduction
Hypoxia-ischemia (HI) is a major perinatal problem that results in severe damage to the brain impairing the normal development of the auditory system. The purpose of the present study is to study the effect ...
Uptake and intracytoplasmic storage of pigmented particles by human CD34+stromal cells/telocytes: endocytic property of telocytes
(Wiley Blackwell, 2014-12)
We studied the phagocytic-like capacity of human CD34+ stromal cells/telocytes (TCs). For this, we examined segments of the colon after injection of India ink to help surgeons localize lesions identified at endoscopy. Our ...
Distribución de las proteínas acrosómicas GCNF Y SP56 en ratones infértiles GOPC y en un modelo de globozoospermia inducida mediante bloque de GOPC.
(2018-07-20)
La infertilidad es un importante problema médico cuyo estudio es de gran interés científico y social. La infertilidad masculina está causada por uno o varios fallos durante la biogénesis del espermatozoide. El modelo murino ...
Role of Antioxidants in Neonatal Hypoxic–Ischemic Brain Injury: New Therapeutic Approaches
(MDPI, 2017-02)
Hypoxic-ischemic brain damage is an alarming health and economic problem in spite of the advances in neonatal care. It can cause mortality or detrimental neurological disorders such as cerebral palsy, motor impairment and ...