dc.contributor.author | Han, C. | |
dc.contributor.author | Vinsky, M. | |
dc.contributor.author | Aldai Elkoro-Iribe, Noelia | |
dc.contributor.author | Dugan, M. E. R. | |
dc.contributor.author | McAllister, T.A. | |
dc.contributor.author | Li, C. | |
dc.date.accessioned | 2012-11-30T12:41:27Z | |
dc.date.available | 2012-11-30T12:41:27Z | |
dc.date.issued | 2013-03 | |
dc.identifier.citation | Meat science 93(3) : 429-436 (2013) | es |
dc.identifier.issn | 0309-1740 | |
dc.identifier.uri | http://hdl.handle.net/10810/9117 | |
dc.description.abstract | Two previously reported DNA polymorphisms of sterol regulatory element binding transcription factor 1 (SREBP1) and liver X receptor alpha (LXRα) and two DNA
polymorphisms of fatty acid desaturase 1 (FADS1) were evaluated for associations with
fatty acids in brisket adipose tissue of Canadian cross-bred beef steers. The polymorphism of 84 bp insert/deletion in intron 5 of SREBP1 was significantly associated with the concentration of 9c C17:1 (P=0.013). The G>A single nucleotide polymorphism (SNP) in the exon 4 of LXRα gene was associated with the concentration of 9c, 11t C18:2 (P=0.04), sum of conjugated linoleic acids (CLA) (P=0.025) and 11c C20:1(P=0.042). Two DNA polymorphisms in the promoter region of FADS1, deletion/insertion of ->GTG in rs133053720 and SNP A>G in rs42187276, were significantly associated with concentrations of C17:0 iso, C17:0 ai, total branched chain fatty acids (BFA), 12t C18:1, 13t/14t C18:1, 15t C18:1, and 13c C18:1 (P<0.05). Further studies are needed to validate the associations and to delineate the roles of the gene polymorphisms in determining the fatty acid composition in beef tissues. | en |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | fatty acid | en |
dc.subject | beef | en |
dc.subject | sterol regulatory element binding protein 1 | en |
dc.subject | liver X receptor alpha | en |
dc.subject | fatty acid desaturase 1 | en |
dc.subject | association | en |
dc.title | Association analyses of DNA polymorphisms in bovine SREBP-1, LXRα,FADS1 genes with fatty acid composition in Canadian commercial crossbred beef steers | en |
dc.type | info:eu-repo/semantics/article | es |
dc.rights.holder | Elsevier | es |
dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0309174012003543 | es |
dc.relation.publisherversion | http://www.journals.elsevier.com/meat-science/ | es |
dc.identifier.doi | 10.1016/j.meatsci.2012.10.006 | |
dc.departamentoes | Farmacia y ciencias de los alimentos | es_ES |
dc.departamentoeu | Farmazia eta elikagaien zientziak | es_ES |
dc.subject.categoria | FOOD SCIENCE AND TECHNOLOGY | |