BackExaminar Artículos por departamento (eus.) "Genetika,antropologia fisikoa eta animalien fisiologia"
Now showing items 41-60 of 256
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Association of TYR SNP rs1042602 with Melanoma Risk and Prognosis
Sevilla Mambrilla, Arrate
; ; ; Izagirre Arribalzaga, Neskuts ; ; ; ; ; ; ; ; Asumendi Mallea, Aintzane ; Boyano López, María Dolores ; Alonso Alegre, Santos (MDPI, 2022-12-01)
Cutaneous melanoma is the most aggressive of skin tumors. In order to discover new biomarkers that could help us improve prognostic prediction in melanoma patients, we have searched for germline DNA variants associated ... -
Authoritative subspecies diagnosis tool for European honey bees based on ancestryinformative SNPs
Momeni, Jamal; Parejo Feuz, Melanie; Nielsen, Rasmus O.; Langa Arranz, Jorge Eliseo; Montes Asperilla, Iratxe ; Papoutsis, Laetitia; Farajzadeh, Leila; Bendixen, Christian; Căuia, Eliza; Charrière, Jean-Daniel; Coffey, Mary F.; Costa, Cecilia; Dall’Olio, Raffaele; De la Rúa, Pilar; Drazic, M.Maja; Filipi, Janja; Galea, Thomas; Golubovski, Miroljub; Gregorc, Ales; Grigoryan, Karina; Hatjina, Fani; Ilyasov, Rustem; Ivanova, Evgeniya; Janashia, Irakli; Kandemir, Irfan; Karatasou, Aikaterini; Kekecoglu, Meral; Kezic, Nikola; Sz.Matray, Enikö; Mifsud, David; Moosbeckhofer, Rudolf; Nikolenko, Alexei G.; Papachristoforou, Alexandros; Petrov, Plamen; Pinto, M. Alice; Poskryakov, Aleksandr V.; Sharipov, Aglyam Y.; Siceanu, Adrian; Soysal, M.Ihsan; Uzunov, Aleksandar; Zammit-Mangion, Marion; Vingborg, Rikke; Bouga, Maria; Kryger, Per; Meixner, Marina D.; Estomba Recalde, Miren Andone (BMC, 2021-02-03)
Background With numerous endemic subspecies representing four of its five evolutionary lineages, Europe holds a large fraction of Apis mellifera genetic diversity. This diversity and the natural distribution range have ... -
Automatically exposing OpenLifeData via SADI semantic Web Services
; ; ; ; Egaña Aranguren, Mikel; ; (Biomed Central, 2014-11-19)
Background: Two distinct trends are emerging with respect to how data is shared, collected, and analyzed within the bioinformatics community. First, Linked Data, exposed as SPARQL endpoints, promises to make data easier ... -
Baseline tissue concentrations of metal in aquatic oligochaetes: field and laboratory approaches.
Méndez Fernández, Leire; Martínez Madrid, Maite ; ; (Elsevier, 2017-02-04)
Metal tissue residue evaluation in benthic macroinvertebrates is an important component of an integrated approach to ecological risk assessment of metals and metalloids in the Nalón River basin (North Spain), where historic ... -
BRAF V600E mutational load as a prognosis biomarker in malignant melanoma
Sevilla Mambrilla, Arrate; ; Ezcurra García Unzueta, Pilar Ariadna ; ; ; ; ; ; ; ; Asumendi Mallea, Aintzane ; ; Boyano López, María Dolores ; Alonso Alegre, Santos (Public Library Science, 2020-03-13)
Analyzing the mutational load of driver mutations in melanoma could provide valuable information regarding its progression. We aimed at analyzing the heterogeneity of mutational load of BRAF V600E in biopsies of melanoma ... -
Celiac Diasease-associated lncRNA Named HCG14 Regulates NOD1 Expression in Intestinal Cells
; ; ; ; ; ; Fernández Jiménez, Nora; Irastorza Terradillos, Iñaki Xarles ; Castaño González, Luis Antonio ; Bilbao Catalá, José Ramón (Wiley, 2018-08-01)
Objective: The aim of the study is to identify additional celiac disease associated loci in the major histocompatibility complex (MHC) independent from classical HLA risk alleles (HLA-DR3-DQ2) and to characterize their ... -
Celiac disease in the Mediterranean area
Tucci, Francesca; Astarita, Luca; Abkari, Abdelhak; Abu-Zekry, Mona; Attard, Thomas; Ben Hariz, Mongi; Bilbao Catalá, José Ramón; Boudraa, Ghazalia; Boukthir, Samir; Costa, Stefano; Djurisic, Veselinka; Hugot, Jean-Pierre; Irastorza Terradillos, Iñaki Xarles ; Kansu, Aydan; Kolacek, Sanja; Magazzu, Giuseppe; Micetic-Turk, Dusanka; Misak, Zrinjka; Roma, Eleftheria; Rossi, Pasqualino; Terzic, Selma; Velmishi, Virtut; Arcidiaco, Carmela; Auricchio, Renata; Greco, Luigi; (BioMed Central, 2014-02)
Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe ... -
Changing genetic architecture of body mass index from infancy to early adulthood: an individual based pooled analysis of 25 twin cohorts
(Nature, 2022-10)Background Body mass index (BMI) shows strong continuity over childhood and adolescence and high childhood BMI is the strongest predictor of adult obesity. Genetic factors strongly contribute to this continuity, but it is ... -
Chromosomes trapped in micronuclei are liable to segregation errors
; García Santisteban, Iraia; ; ; (Company Biologist LTD, 2018-07-09)
DNA in micronuclei is likely to get damaged. When shattered DNA from micronuclei gets reincorporated into the primary nucleus, aberrant rearrangements can take place, a phenomenon referred to as chromothripsis. Here, we ... -
CircRNAome of Childhood Acute Lymphoblastic Leukemia: Deciphering Subtype-Specific Expression Profiles and Involvement in TCF3::PBX1 ALL
Gutiérrez Camino, Ángela; ; ; ; ; ; ; ; ; López López, Elixabet ; ; ; ; ; ; ; (MDPI, 2024-01-25)
Childhood B-cell acute lymphoblastic leukemia (B-ALL) is a heterogeneous disease comprising multiple molecular subgroups with subtype-specific expression profiles. Recently, a new type of ncRNA, termed circular RNA (circRNA), ... -
Circulating MiRNAs As Biomarkers In Diffuse Large B-Cell lymphoma: A Systematic Review
López Santillán, María; Larrabeiti Etxebarria, Ane; Arzuaga Mendez, Javier; López López, Elixabet; García-Orad Carles, África (2018-04-27)
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Combined Analysis of Methylation and Gene Expression Profiles in Separate Compartments of Small Bowel Mucosa Identified Celiac Disease Patients' Signatures
Cielo, D.; Galatola, M.; Fernández Jiménez, Nora; De Leo, L.; García Etxebarria, Koldo; Loganes, C.; Tommasini, A.; Not, T.; Auricchio, Renata; Greco, Luigi; Bilbao Catalá, José Ramón (Nature Publishing Group, 2019-07-10)
By GWAS studies on celiac disease, gene expression was studied at the level of the whole intestinal mucosa, composed by two different compartments: epithelium and lamina propria. Our aim is to analyse the gene-expression ... -
Combined Fluorescent-Chromogenic In Situ Hybridization for Identification and Laser Microdissection of Interphase Chromosomes
Paz Gandiaga, Nerea; Zabala, Amaia; Royo, Félix; García-Orad Carles, África; Zugaza Gurruchaga, José Luis ; Parada, Luis A. (Public Library of Science, 2013)
Chromosome territories constitute the most conspicuous feature of nuclear architecture, and they exhibit non-random distribution patterns in the interphase nucleus. We observed that in cell nuclei from humans with Down ... -
Comparison of predicted body fat percentage from anthropometric methods and from impedance in university students
; Rocandio Pablo, Ana María; Ansotegui Alday, Laura; Herrera, Héctor; Salces Beti, Itziar; (Cambridge University Press, 2004-11)
The objective of the present study was to compare different methods for evaluating body fat percentage (BF%) (anthropometric methods and bioelectrical impedance analysis) in university students. Subjects were 653 healthy ... -
Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation
; ; García de Galdeano Zaldivar, María Alicia; Boyano López, María Dolores ; ; ; ; Izagirre Arribalzaga, Neskuts ; De la Rúa Vaca, Concepción ; Alonso Alegre, Santos (Public Library Science, 2015-08-05)
We analysed the whole-genome transcriptional profile of 6 cell lines of dark melanocytes (DM) and 6 of light melanocytes (LM) at basal conditions and after ultraviolet-B (UVB) radiation at different time points to investigate ... -
Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population
Gutiérrez Camino, Ángela; ; ; ; ; ; ; García-Orad Carles, África (Public Library Science, 2017-05-08)
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the long noncoding RNA (lncRNA) known as ANRIL (or CDKN2B-AS), was associated with childhood acute lymphoblastic leukemia (ALL) ... -
Connectivity and Population Structure of Albacore Tuna Across Southeast Atlantic and Southwest Indian Oceans Inferred from Multidisciplinary Methodology
Nikolic, Natacha; Montes Asperilla, Iratxe; Lalire, Maxime; Puech, Alexis; Bodin, Nathalie; Arnaud-Haond, Sophie; Kerwath, Sven; Corse, Emmanuel; Gaspar, Philippe; Hollanda, Stephanie; Bourjea, Jerome; West, Wendy; Bonhommeau, Sylvain (Nature, 2020-09-24)
Albacore tuna (Thunnus alalunga) is an important target of tuna fisheries in the Atlantic and Indian Oceans. The commercial catch of albacore is the highest globally among all temperate tuna species, contributing around ... -
Detailed dissection of UBE3A-mediated DDI1 ubiquitination.
Elu Arantzamendi, Nagore; Osinalde Moraleja, Nerea ; ; Ramírez Sánchez, Juan Manuel ; ; ; Rodríguez Pérez, José Antonio ; Arizmendi Bastarrika, Jesús María ; Mayor Martínez, Ugo (Frontiers, 2019-05-03)
The ubiquitin E3 ligase UBE3A has been widely reported to interact with the proteasome, but it is still unclear how this enzyme regulates by ubiquitination the different proteasomal subunits. The proteasome receptor DDI1 ... -
Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy
Axpe Iza, Eneko; López Euba, Tamara; Castellanos Rubio, Ainara; Mérida Sanz, David; ; Plaza-Izurieta, Leticia; Fernández-Jiménez, Nora; Plazaola Muguruza, Fernando; Bilbao Catalá, José Ramón (Public Library of Science, 2014-01-02)
Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ... -
Detection of Phylogenetically Informative Polymorphisms in the Entire Euchromatic Portion of Human Y Chromosome From a Sardinian Sample
Francalacci, Paolo; Sanna, Daria; Useli, Antonella; Berutti, Riccardo; Barbato, Mario; Whalen, Michael B.; Angius, Andrea; Sidore, Carlo; Alonso Alegre, Santos; Tofanelli, Sergio; Cucca, Francesco (Biomed Central, 2015-04-30)
BACKGROUND: Next-Generation Sequencing methods have led to a great increase in phylogenetically useful markers within the male specific portion of the Y chromosome, but previous studies have limited themselves to the study ...