BackBrowsing Artículos by Title
Now showing items 6631-6650 of 10330
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Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties
Cochet, Florent; Facchini, Fabio A.; Zaffaroni, Lenny; Billod, Jean-Marc; Coelho, Helena; Holgado, Aurora; Braun, Harald; Beyaert, Rudi; Jerala, Roman; Jiménez Barbero, Jesús
; Martin-Santamaria, Sonsoles; Peri, Francesco (Nature Publishing, 2019-01-29)
New monosaccharide-based lipid A analogues were rationally designed through MD-2 docking studies. A panel of compounds with two carboxylate groups as phosphates bioisosteres, was synthesized with the same glucosamine-bis-succinyl ... -
Novel Ce-modified cobalt catalysts supported over α-Al2O3 open cell foams for lean methane oxidation
Choya Atencia, Andoni; Gudyka, Sylwia; ; Gutiérrez Ortiz, José Ignacio ; Kotarba, Andrzej; López Fonseca, Rubén (Elsevier, 2022-02)
[EN] A series of CeO2-modified Co3O4 catalysts supported over alpha-Al2O3 foams was prepared by solution combustion synthesis and examined for the lean methane oxidation. Two different fuels were used namely, urea and ... -
Novel CircRNA Discovery in Sheep Shows Evidence of High Backsplice Junction Conservation
Varela Martínez, Endika; Corsi, Giulia I.; Anthon, Christian; Gorodkin, Jan; Jugo Orrantia, Begoña Marina (Springer Nature, 2021-01-11)
Circular RNAs (circRNAs) are covalently closed circular non-coding RNAs. Due to their structure, circRNAs are more stable and have longer half-lives than linear RNAs making them good candidates for disease biomarkers. ... -
Novel compound heterozygous mutations of CLDN16 in a patient with familial hypomagnesemia with hypercalciuria and nephrocalcinosis
Monnier, Xavier; García Castaño, Alejandro; Perdomo Ramírez, Ana; Vall Palomar, Mònica; Ramos Trujillo, Elena; Madariaga Domínguez, Leire; Ariceta, Gema; Claverie Martín, Félix (Wiley, 2020-11)
Background: Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is an autosomal recessive tubulopathy characterized by excessive urinary wasting of magnesium and calcium, bilateral nephrocalcinosis, ... -
Novel control algorithm for MPPT with Boost converters in photovoltaic systems
; López Guede, José Manuel; Barambones Caramazana, Oscar ; ; (Elsevier, 2017-07)
The great advances in efficiency and performance of photovoltaic modules would not be very useful if they do not work close to their maximum power point (MPP). In this paper a novel Sliding Mode Control (SMC) based algorithm ... -
Novel Dextran-Supported Biological Probes Decorated with Disaccharide Entities for Investigating the Carbohydrate-Protein Interactions of Gal-3.
Rahkila, Jani; Ekholm, Filip S.; Ardá, Ana; Delgado, Sandra; Savolainen, Johannes; Jiménez Barbero, Jesús ; Leino, Reko (Wiley, 2018-11-30)
The quest for novel natural-like biomolecular probes that can be used to gain information on biological recognition events is of topical interest to several scientific areas. In particular, the recognition of carbohydrates ... -
Novel equation to determine the hepatic triglyceride concentration in humans by MRI: diagnosis and monitoring of NAFLD in obese patients before and after bariatric surgery
Jiménez Agüero, Raúl; Emparanza, José Ignacio; Beguiristain Gómez, Adolfo; Bujanda Fernández de Pierola, Luis; Alustiza Echeberria, José María; García, Elisabeth; Hijona Muruamendiaraz, Elizabeth; Gallego, Lander; Sanchez Gonzalez, Javier; Perugorria Montiel, María Jesús; Asensio, José I; Larburu Echaniz, Santiago; Garmendia Antin, Maddi ; Larzabal, Mikel; Portillo Baquedano, María Puy ; Aguirre López, Leixuri ; Bañales Asurmendi, Jesús María (Biomed Central, 2014-08-26)
Background: Non-alcoholic fatty liver disease (NAFLD) is caused by abnormal accumulation of lipids within liver cells. Its prevalence is increasing in developed countries in association with obesity, and it represents a ... -
Novel Evidence hat Attributing Affectively Salient Signal to Random Noise Is Associated with Psychosis
Catalán Alcántara, Ana; Simons, Claudia J. P.; Bustamante Madariaga, Sonia; Drukker, Marjan; Madrazo, Aranzazu; González de Artaza Lavesa, Maider; Gorostiza, Iñigo; Van Os, Jim; González Torres, Miguel Ángel (Public Library Science, 2014-07-14)
We wished to replicate evidence that an experimental paradigm of speech illusions is associated with psychotic experiences. Fifty-four patients with a first episode of psychosis (FEP) and 150 healthy subjects were examined ... -
Novel genes and sex differences in COVID-19 severity
Castaño González, Luis Antonio; ; ; (Oxford University Press, 2022-11)
Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE ... -
Novel Golden Lipid Nanoparticles with Small Interference Ribonucleic Acid for Substrate Reduction Therapy in Fabry Disease
Beraza Millor, Marina; Rodríguez Castejón, Julen ; Miranda Gómez, Jonatan ; Del Pozo Rodríguez, Ana ; ; Solinís Aspiazu, María Ángeles (MDPI, 2023-07-12)
Substrate reduction therapy (SRT) has been proposed as a new gene therapy for Fabry disease (FD) to prevent the formation of globotriaosylceramide (Gb3). Nanomedicines containing different siRNA targeted to Gb3 synthase ... -
Novel hybrid organic/inorganic poly(thiourethane) covalent adaptable networks
(Elsevier, 2022-07)Organic-inorganic hybrid materials combine the advantages of both phases: hardness and strength of inorganic phase and elasticity and toughness of the organic matrix. In the present study, we have prepared nanocomposites ... -
Novel Hydrogels of Chitosan and Poly(vinyl alcohol) Reinforced with Inorganic Particles of Bioactive Glass
; ; Meaurio Arrate, Emiliano; ; ; Sarasua Oiz, José Ramón (MDPI, 2021-02-25)
Chitosan (CS) and poly(vinyl alcohol) (PVA) hydrogels, a polymeric system that shows a broad potential in biomedical applications, were developed. Despite the advantages they present, their mechanical properties are ... -
Novel Loci for Childhood Body Mass Index and Shared Heritability with Adult Cardiometabolic Traits
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Bilbao Catalá, José Ramón; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Public Library Science, 2020-10-12)
The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed ... -
Novel Mean-Type Inequalities via Generalized Riemann-Type Fractional Integral for Composite Convex Functions: Some Special Examples
; ; ; ; ; De la Sen Parte, Manuel; (MDPI, 2023-02-10)
This study deals with a novel class of mean-type inequalities by employing fractional calculus and convexity theory. The high correlation between symmetry and convexity increases its significance. In this paper, we first ... -
Novel Papillomaviruses in Free-Ranging Iberian Bats: No Virus-Host Co-evolution, No Strict Host Specificity, and Hints for Recombination
García Pérez, Raquel; Ibáñez, Carlos; Godínez, José M.; Aréchiga, Nidia; Garín Atorrasagasti, Ignacio; Pérez Suárez, Gonzalo; De Paz, Oscar; Juste, Javier; Echevarría, Juan E.; Bravo, Ignacio G. (Oxford University Press, 2014)
Papillomaviruses (PVs) are widespread pathogens. However, the extent of PV infections in bats remains largely unknown. This work represents the first comprehensive study of PVs in Iberian bats. We identified four novel PVs ... -
Novel phosphine sulphide gold(I) complexes: topoisomerase I inhibitors and antiproliferative agents
; ; ; ; Rubiales Alcaine, María Gloria; ; Palacios Gambra, Francisco Javier ; Alonso Pérez, Concepción Estibaliz (RSC, 2020-05-20)
This work describes the synthesis of the gold(I) complexes of phosphine sulphides. The formation of these new derivatives has been confirmed by X-ray crystallography. The coordination of gold(I) with the sulphur atom of ... -
Novel Pixelwise Co-Registered Hematoxylin-Eosin and Multiphoton Microscopy Image Dataset for Human Colon Lesion Diagnosis
Picón Ruiz, Artzai; Terradillos Fernández, Elena; Sánchez Peralta, Luisa F.; Mattana, Sara; Cicchi, Riccardo; Blover, Benjamin J.; Arbide del Río, Nagore; Velasco Arteche, Jacques; Etxezarraga Zuluaga, María Carmen; Pavone, Francesco S.; Garrote Contreras, Estíbaliz; López Saratxaga, Cristina (Elsevier, 2022-02-07)
Colorectal cancer presents one of the most elevated incidences of cancer worldwide. Colonoscopy relies on histopathology analysis of hematoxylin-eosin (H&E) images of the removed tissue. Novel techniques such as multi-photon ... -
Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation
; ; ; ; ; Isla Ruiz, Arantxazu; (MDPI, 2020-01-09)
Antimicrobial treatment in critically ill patients remains challenging. The aim of this study was to develop a population pharmacokinetic model for linezolid in critically ill patients and to evaluate the adequacy of ... -
Novel Sol-Gel Route to Prepare Eu3+-Doped 80SiO2-20NaGdF4 Oxyfluoride Glass-Ceramic for Photonic Device Applications
; ; ; ; ; Balda de la Cruz, Rolindes; (MDPI, 2023-03-05)
Oxyfluoride glass-ceramics (OxGCs) with the molar composition 80SiO2-20(1.5Eu3+: NaGdF4) were prepared with sol-gel following the “pre-crystallised nanoparticles route” with promising optical results. The preparation of ... -
Novel Thermal Management Strategy for Improved Inverter Reliability in Electric Vehicles
Trancho Olabarri, Elena; Ibarra Basabe, Edorta ; ; ; ; (MDPI, 2020-11-12)
Requirements for electric vehicle (EV) propulsion systems—i.e., power density, switching frequency and cost—are becoming more stringent, while high reliability also needs to be ensured to maximize a vehicle’s life-cycle. ...