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Excipient-Free Inhalable Microparticles of Azithromycin Produced by Electrospray: A Novel Approach to Direct Pulmonary Delivery of Antibiotics
(MDPI, 2021-11-16)
Inhalation therapy offers several advantages in respiratory disease treatment. Azithromycin is a macrolide antibiotic with poor solubility and bioavailability but with a high potential to be used to fight lung infections. ...
Integrated biological response to environmentally-relevant concentration of amitriptyline in Sparus aurata
(Elsevier, 2021-11)
[EN]Amitriptyline (AMI) is a commonly tricyclic antidepressant to treat depression, anxiety, and other conditions. Like many other pharmaceuticals, AMI and its by-products are incompletely removed during wastewater treatment ...
Microstructure and Phase Formation of Novel Al80Mg5Sn5Zn5X5 Light-Weight Complex Concentrated Aluminum Alloys
(MDPI, 2021-12-01)
In this work, three novel complex concentrated aluminum alloys were developed. To investigate the unexplored region of the multicomponent phase diagrams, thermo-physical parameters and the CALPHAD method were used to ...
Band Structure and Energy Level Alignment of Chiral Graphene Nanoribbons on Silver Surfaces
(MDPI, 2021-12-06)
Chiral graphene nanoribbons are extremely interesting structures due to their narrow band gaps and potential development of spin-polarized edge states. Here, we study their band structure on low work function silver surfaces. ...
Uptake and Effects of Graphene Oxide Nanomaterials Alone and in Combination with Polycyclic Aromatic Hydrocarbons in Zebrafish
(Elsevier, 2021-06-25)
Because of its surface characteristics, once in the aquatic environment, graphene could act as a carrier of pollutants, such as polycyclic aromatic hydrocarbons (PAHs), to aquatic organisms. In this study we aimed to (1) ...
Fast-running theropods tracks from the Early Cretaceous of La Rioja, Spain
(Nature Research, 2021-12-09)
[EN]Theropod behaviour and biodynamics are intriguing questions that paleontology has been trying to resolve for a long time. The lack of extant groups with similar bipedalism has made it hard to answer some of the questions ...
The role of production factors on landings heterogeneity between EU countries
(Elsevier, 2021-10)
[EN]Distribution of natural resources is considered to be a key aspect in ensuring the success of conservation policies. The Common Fisheries Policy, implemented by the European Union (EU), is an example of long-term ...
Design of a Nasal Spray Based on Cardiospermum halicacabum Extract Loaded in Phospholipid Vesicles Enriched with Gelatin or Chondroitin Sulfate
(MDPI, 2021-11-04)
The extract of Cardiospermum halicacabum L. (C. halicacabum) obtained from flower, leaf and vine was loaded into modified phospholipid vesicles aiming at obtaining sprayable, biocompatible and effective nasal spray ...
Prevalence of Anxiety in Dental Students during the COVID-19 Outbreak: A Meta-Analysis
(MDPI, 2021-10-19)
Background: Since the onset of the COVID-19 pandemic, the psychological state of university students has been a cause for concern. In particular, odontology students have experienced symptoms of anxiety due to the closure ...
Naphthyridine Derivatives Induce Programmed Cell Death in Naegleria fowleri
(MDPI, 2021-10-01)
Primary amoebic encephalitis (PAM) caused by the opportunistic pathogen Naegleria fowleri is characterized as a rapid and lethal infection of the brain which ends in the death of the patient in more than 90% of the reported ...