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Combustion of a Solid Recovered Fuel (SRF) Produced from the Polymeric Fraction of Automotive Shredder Residue (ASR)
(MDPI, 2021-11-03)
The use of alternative fuels derived from residues in energy-intensive industries that rely on fossil fuels can cause considerable energy cost savings, but also significant environmental benefits by conserving non-renewable ...
Oligodendroglial Energy Metabolism and (re)Myelination
(MDPI, 2021-03-13)
Central nervous system (CNS) myelin has a crucial role in accelerating the propagation of action potentials and providing trophic support to the axons. Defective myelination and lack of myelin regeneration following ...
Sequential crystallization and multi-crystalline morphology in PE-b-PEO-b-PCL-b-PLLA tetrablock quarterpolymers
(ACS, 2021-08-10)
We investigate for the first time the morphology and crystallization of two novel tetrablock quarterpolymers of
polyethylene (PE), poly(ethylene oxide) (PEO), poly(ε-caprolactone) (PCL), and poly(L-lactide) (PLLA) with ...
Specific Hippocampal Interneurons Shape Consolidation of Recognition Memory
(Cell Press, 2020-08-18)
A complex array of inhibitory interneurons tightly controls hippocampal activity, but how such diversity specifically affects memory processes is not well understood. We find that a small subclass of type 1 cannabinoid ...
The Role of lncRNAs in Gene Expression Regulation through mRNA Stabilization
(MDPI, 2021-01-05)
mRNA stability influences gene expression and translation in almost all living organisms, and the levels of mRNA molecules in the cell are determined by a balance between production and decay. Maintaining an accurate balance ...
Analysis of Acetylcholinesterase Activity in Cell Membrane Microarrays of Brain Areas as a Screening Tool to Identify Tissue Specific Inhibitors
(MDPI, 2021-03-23)
Acetylcholinesterase (AChE) is responsible for hydrolyzing the acetylcholine neurotransmitter, bringing an end point to cholinergic neurotransmission. Thus, AChE is the primary target of a wide spectrum of compounds used ...
The Effect of the Laser Incidence Angle in the Surface of L-PBF Processed Parts
(MDPI, 2020-10-24)
The manufacture of multiple parts on the same platform is a common procedure in the Laser Powder Bed Fusion (L-PBF) process. The main advantage is that the entire working volume of the machine is used and a greater number ...
Surface Activation of Titanium Dental Implants by Using UVC-LED Irradiation
(MDPI, 2021-03-05)
Organic contaminants significantly limit the bioactivity of titanium implants, resulting in the degradation known as the ageing of titanium. To reactivate the surfaces, they can be photofunctionalized, i.e., irradiated ...
Structure of HIV-1 gp41 with its Membrane Anchors Targeted by Neutralizing Antibodies
(eLife Sciences, 2021-04-19)
The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate ...
Synucleinopathy alters nanoscale organization anddiffusion in the brain extracellular space throughhyaluronan remodeling
(Nature, 2020-07-10)
In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains ...