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Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle
(Public Library Science, 2015-12-15)
Cannabinoid CB1 receptors peripherally modulate energy metabolism. Here, we investigated the role of CB1 receptors in the expression of glucose/pyruvate/tricarboxylic acid (TCA) metabolism in rat abdominal muscle. ...
Dipeptidyl-Peptidase IV Activity Is Correlated with Colorectal Cancer Prognosis
(Public Library Science, 2015-03-19)
Background
Dipeptidyl-peptidase IV (EC 3.4.14.5) (DPPIV) is a serine peptidase involved in cell differentiation, adhesion, immune modulation and apoptosis, functions that control neoplastic transformation. Previous ...
Two new species of Zospeum Bourguignat, 1856 from the Basque-Cantabrian Mountains, Northern Spain (Eupulmonata, Ellobioidea, Carychiidae)
(Pensoft Publishers, 2015)
Two new species of the genus Zospeum Bourguignat, 1856 are described from caves in the Sierra de Aitzgorri (Gipuzkoa) and the Sierra Salvada (Burgos) in Northern Spain. The taxa Z. vasconicum sp. n. and Z. zaldivarae sp. ...
Efficient Synthesis of Single-Chain Polymer Nanoparticles via Amide Formation
(Hindawi Publishing, 2015)
Single-chain technology (SCT) allows the transformation of individual polymer chains to folded/collapsed unimolecular soft nanoparticles. In this work we contribute to the enlargement of the SCT toolbox by demonstrating ...
Snomed CT in a Language Isolate: an Algorithm for a Semiautomatic Translation
(Biomed Central, 2015-06-15)
Background:: The Systematized Nomenclature of Medicine - Clinical Terms (SNOMED CT) is officially released in English and Spanish. In the Basque Autonomous Community two languages, Spanish and Basque, are official. The ...
Lethal Interpersonal Violence in the Middle Pleistocene
(Public Library Science, 2015-05-27)
Evidence of interpersonal violence has been documented previously in Pleistocene members of the genus Homo, but only very rarely has this been posited as the possible manner of death. Here we report the earliest evidence ...
Unplugging: Deconstructing the Smart City Journal of Urban Technology
(Taylor & Francis, 2015-03-16)
This paper explores the subtle notion of unplugging to critically analyze the technological determinism of the Smart City. This exploration suggests that being digitally connected should not be perceived as gaining social ...
Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation
(Public Library Science, 2015-08-05)
We analysed the whole-genome transcriptional profile of 6 cell lines of dark melanocytes (DM) and 6 of light melanocytes (LM) at basal conditions and after ultraviolet-B (UVB) radiation at different time points to investigate ...
The Forbidden Quantum Adder
(Nature Publishing Group, 2015-07-08)
Quantum information provides fundamentally different computational resources than classical information. We prove that there is no unitary protocol able to add unknown quantum states belonging to different Hilbert spaces. ...
Scalable quantum memory in the ultrastrong coupling regime
(Nature Publishing, 2015-03-02)
Circuit quantum electrodynamics, consisting of superconducting artificial atoms coupled to on-chip resonators, represents a prime candidate to implement the scalable quantum computing architecture because of the presence ...