Search
Now showing items 191-200 of 239
Genetic Variants and Hamstring Injury in Soccer: An Association and Validation Study
(American College of Sports Medicine, 2018-02)
Purpose: This study aimed to investigate the association of candidate single nucleotide polymorphisms (SNP) with noncontact hamstring muscle injuries in elite soccer players and to create and validate a model to assess the ...
Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora
(Nature Publishing Group, 202016-10-)
When cells in G2 phase are challenged with DNA damage, several key mitotic regulators such as Cdk1/Cyclin B, Aurora A and Plk1 are inhibited to prevent entry into mitosis. Here we have studied how inhibition of Plk1 is ...
Influence of genetic polymorphisms on arsenic methylation efficiency during pregnancy: Evidence from a Spanish birth cohort
(Elsevier, 2023-07-24)
Inorganic arsenic (iAs) is a widespread toxic metalloid. It is well-known that iAs metabolism and its toxicity are mediated by polymorphisms in AS3MT and other genes. However, studies during pregnancy are scarce. We aimed ...
Mutations in the ‘Fingers’ subdomain of the deubiquitinase USP1 modulate its function and activity
(FEBS Press, 2016-01-13)
Ubiquitin-specific protease (USP)1 is a member of the USP family of deubiquitinating enzymes. Efficient USP1 activity requires binding to its cofactor USP1-associated factor 1 (UAF1), and the USP1-UAF1 deubiquitinase complex ...
Growth and Physiological Performance in Growth Phenotypes of the Carpet Shell Clam (Ruditapes decussatus) Fed Diets of Variable Lipid/Carbohydrate Ratios
(Hindawi, 2023-08-12)
Mixed suspensions of phytoplankton and yeast cells in different proportions were designed to achieve diets with a range of
variation (0.6–2.2) in the ratio of lipid to carbohydrate while maintaining protein content constant. ...
Stoichiometry of growth under variable scenarios of nutrient limitation: Differential homeostasis of body composition among growth phenotypes of the Manila clam
(Elsevier, 2024-02-07)
Fast- and slow-growing phenotypes from two separate breeding families of the Manila clam (Ruditapes philippinarum)
were alternatively fed two monoalgal diets with high and low N content (C:N ratios of 4.9 and 13.5,
res ...
High Throughput Fluorescence-Based In Vitro Experimental Platform for the Identification of Effective Therapies to Overcome Tumour Microenvironment-Mediated Drug Resistance in AML
(MDPI, 2023-03-27)
The interactions between Acute Myeloid Leukaemia (AML) leukemic stem cells and the bone marrow (BM) microenvironment play a critical role during AML progression and resistance to drug treatments. Therefore, the identification ...
Elemental C and N balances evidence stoichiometric adjustments to dietary protein content in growth phenotypes of the Manila clam (Ruditapes philippinarum)
(Elsevier, 2022-03-24)
Juveniles from two separately bred families of the Manila clam Ruditapes philippinarum were used to constitute
fast (F)- and slow (S)-growing groups by size segregation. The growth phenotypes that resulted from these ...
From classical to nonparametric growth models: Towards comprehensive modelling of mussel growth patterns
(Elsevier, 2017-03-18)
Understanding biological processes, such as growth, is crucial to development management and sustainability plans for bivalve populations. Von Bertalanffy and Gompertz models have been commonly used to fit bivalve growth. ...
A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells
(Frontiers Media, 2023-02)
IntroductionMost of the disease-associated single nucleotide polymorphisms (SNPs) lie in non- coding regions of the human genome. Many of these variants have been predicted to impact the expression and function of long ...