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Pharmacokinetic/pharmacodynamic analysis as a tool for surveillance of the activity of antimicrobials against Pseudomonas aeruginosa strains isolated in critically ill patients
(Elsevier, 2018-10-11)
Introduction: To evaluate the changes in the susceptibility of Pseudomonas aeruginosa overtime (2000–2017) against antimicrobials used in an intensive care unit of a Spanish tertiaryhospital, and to compare them with the ...
Current status and perspectives of the official sensory control methods in protected designation of origin food products and wines
(Elsevier Ltd., 2018-02-03)
Protected Designation of Origin (PDO) is part of the regulated quality schemes in the European Union
(EU). Producers of PDO food products and wines have to present EU authorities a technical specification
of their product, ...
Does consumer liking fit the sensory quality assessed by trained panelists in traditional food products? A study on PDO Idiazabal cheese
(Wiley, 2018-03-30)
The aim of this work was to study the degree of agreement between consumer liking and the sensory quality scored by the trained panel in charge of the quality control of a traditional product (PDO Idiazabal cheese). Nine ...
Population pharmacokinetics of daptomycin in critically ill patients
(Elsevier, 2018-03-20)
Daptomycin has shown activity against a wide range of Gram-positive bacteria; however, the approved dosages usually seem insufficient for critically ill patients. The aim of this study was to develop a population pharmacokinetic ...
Involvement of autophagy in the beneficial effects of resveratrol in hepatic steatosis treatment. A comparison with energy restriction
(RSC, 2018-06-26)
Autophagy eliminates damaged cellular components. In the liver, it has been proposed that it mediates the breakdown of lipid droplets. This study aimed to compare the involvement of autophagy and the oxidative status in ...
Gene delivery in the cornea: in vitro and ex vivo evaluation of solid lipid nanoparticle-based vectors
(Future Medicine, 2018-08-01)
Inflammation is a process that underlies sight-threatening ocular surface
diseases, and gene supplementation with the plasmid that encodes for interleukin-10 (p-
IL10) will allow the sustained de novo synthesis of the ...