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Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons
(Biomed Central, 2016-11-18)
Background: Mutations in leucine-rich repeat kinase 2 (LRRK2) contribute to both familial and idiopathic forms of Parkinson's disease (PD). Neuroinflammation is a key event in neurodegeneration and aging, and there is ...
High Expression of Endogenous Retroviral Envelope Gene in the Equine Fetal Part of the Placenta
(Public Library Science, 2016-05-13)
Endogenous retroviruses (ERVs) are proviral phases of exogenous retroviruses that have co-evolved with vertebrate genomes for millions of years. Previous studies have identified the envelope (env) protein genes of retroviral ...
Analysis of the Channel Influence to Power Line Communications Based on ITU-T G.9904 (PRIME)
(MDPI, 2016-01)
ITU-T G.9904 standard, also known as PoweRline Intelligent Metering Evolution (PRIME), is a Power Line Communications standard for advanced metering, grid control and asset monitoring defined by the International ...
Sensing parasites: proteomic and advanced bio-detection alternatives
(Elsevier, 2016-03-16)
[EN] Parasitic diseases have a great impact in human and animal health. The gold standard for the diagnosis of the majority of parasitic infections is still conventional microscopy, which presents important limitations in ...
Adaptive coatings based on polyaniline for direct 2D observation of diffusion processes in microfluidic systems
(Elsevier, 2016-08)
[EN] Therefore the understanding and proper evaluation of the flow and mixing behaviour at microscale becomes a very important issue. In this study, the diffusion behaviour of two reacting solutions of HCI and NaOH were ...
Microcantilever arrays functionalised with spiropyran photoactive moieties as systems to measure photo-induced surface stress changes
(Elsevier, 2016-12)
[EN] Herein we investigate the feasibility of detecting photo-induced surface stress changes using the deflection response of cantilevers. For this purpose, silicon microcantilevers have been functionalised with spiropyran ...
Porous self-protonating spiropyran-based NIPAAm gels with improved reswelling kinetics
(Springer, 2016-02)
[EN] This study focuses on improving the speed ofactuation of poly(N-isopropylacrylamide)-based photoresponsive gels containing copolymerised spiropyran as the photoswitch and acrylic acid as the proton source. The improvement ...
Fluidic flow delay by ionogel passive pumps in microfluidic paper-based analytical devices
(Elsevier, 2016-10-05)
[EN] A new concept for fluid flow manipulation in microfluidic paper-based analytical devices (m-PADs) is presented by introducing ionogel materials as passive pumps. m-PADs were fabricated using a new doubleside contact ...
Nitrogen Source and External Medium pH Interaction Differentially Affects Root and Shoot Metabolism in Arabidopsis
(Frontiers Media, 2016-02-01)
Ammonium nutrition often represents an important growth-limiting stress in plants. Some of the symptoms that plants present under ammonium nutrition have been associated with pH deregulation, in fact external medium pH ...
Snail heterogeneity in clear cell renal cell carcinoma
(Biomed Central, 2016-03-08)
Background: Intratumor heterogeneity may be responsible of the unpredictable aggressive clinical behavior that some clear cell renal cell carcinomas display. This clinical uncertainty may be caused by insufficient sampling, ...