Now showing items 151-155 of 155
Brain White Matter Correlates of Creativity in Schizophrenia: A Diffusion Tensor Imaging Study
(Frontiers Media, 2020-06)
The relationship between creativity and psychopathology has been a controversial research topic for decades. Specifically, it has been shown that people with schizophrenia have an impairment in creative performance. However, ...
Glyceryl trinitrate in first-episode psychosis unmedicated with antipsychotics: A randomised controlled pilot study
There is a pressing need for new classes of treatment for psychosis. A key therapeutic target for novel compounds is the NMDA receptor, which may be modulated by nitric oxide donors such as sodium nitroprusside (SNP). ...
Synucleinopathy alters nanoscale organization anddiffusion in the brain extracellular space throughhyaluronan remodeling
In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains ...
Neurocognitive, social cognitive, and clinical predictors of creativity in schizophrenia
Background: Creativity is considered an essential human accomplishment and a key component for daily life problem solving. It has been suggested that impairment in working memory, cognitive flexibility, and theory of mind ...
P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases
(Frontiers Media, 2020-06-18)
Shortage of oxygen and nutrients in the brain induces the release of glutamate and ATP that can cause excitotoxicity and contribute to neuronal and glial damage. Our understanding of the mechanisms of ATP release and ...