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iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology
(Humana Press, 2018-04)
Gerstmann-Straussler-Scheinker (GSS) syndrome is a fatal autosomal dominant neurodegenerative prionopathy clinically characterized by ataxia, spastic paraparesis, extrapyramidal signs and dementia. In some GSS familiar ...
Retained Austenite Control for the Soft Machining of High-Hardness Tool Steels
(MDPI, 2018-07-23)
Most high-hardness tool steels comprising forming dies require expensive finish machining operations to compensate for the dimensional distortion and surface oxidation caused by the die heat treatment. Precipitation-hardening ...
Quantum-Gravitational Effects on Primordial Power Spectra in Slow-Roll Inflationary Models
(MDPI, 2018-01-08)
We review the computation of the power spectra of inflationary gauge-invariant perturbations in the context of canonical quantum gravity for generic slow-roll models. A semiclassical approximation, based on an expansion ...
Development, characterization and comparisons of targeted and non-targeted metabolomics methods
(Public Library Science, 2018-11-15)
The potential of a metabolomics method to detect statistically significant perturbations in the metabolome of an organism is enhanced by excellent analytical precision, unequivocal identification, and broad metabolomic ...
Combining statistical techniques to predict postsurgical risk of 1-year mortality for patients with colon cancer
(Dove Medical Press, 2018)
Introduction: Colorectal cancer is one of the most frequently diagnosed malignancies and a common cause of cancer-related mortality. The aim of this study was to develop and validate a clinical predictive model for 1-year ...
Black hole solutions in mimetic Born-Infeld gravity
(Springer, 2018-01-23)
The vacuum, static, and spherically symmetric solutions in the mimetic Born-Infeld gravity are studied. The mimetic Born-Infeld gravity is a reformulation of the Eddington-inspired-Born-Infeld (EiBI) model under the mimetic ...
Wear And Friction Evaluation Of Different Tool Steels For Hot Stamping
(Hindawi, 2018-03-26)
The aim of this work is to investigate the durability of tool steels for hot stamping by comparing the wear resistance of three hot work tool steels. Friction and wear behaviours of different tool steels sliding against a ...
Using Genetic Algorithms With Multi-Objective Optimization To Adjust Finite Element Models Of Welded Joints
(MDPI, 2018-04-02)
To ensure realistic results when modeling welded joints using the finite element method (FEM), it is essential to appropriately characterize the thermo-mechanical behavior of the elastic-plastic Finite Element (FE) models. ...
An analytic superfield formalism for tree superamplitudes in D=10 and D=11
(Springer, 2018-05-16)
Tree amplitudes of 10D supersymmetric Yang-Mills theory (SYM) and 11D supergravity (SUGRA) are collected in multi-particle counterparts of analytic on-shell superfields. These have essentially the same form as their chiral ...
Pre-Inflation From The Multiverse: Can It Solve The Quadrupole Problem In The Cosmic Microwave Background?
(Springer, 2018-03-21)
We analyze a quantized toy model of a universe undergoing eternal inflation using a quantum-field-theoretical formulation of the Wheeler-DeWitt equation. This so-called third quantization method leads to the picture that ...