Pd(II)-Catalyzed C-H Acylation of (Hetero)arenes. Recent Advances

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Data
2020-07-16
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Santiago Alvarez, Carlos
Sotomayor Anduiza, María Nuria
Lete Expósito, María Esther
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Molecules 25(14) : (2020) // Article ID 3247
URI
http://hdl.handle.net/10810/45827
Laburpena
Di(hetero)aryl ketones are important motifs present in natural products, pharmaceuticals or agrochemicals. In recent years, Pd(II)-catalyzed acylation of (hetero)arenes in the presence of an oxidant has emerged as a catalytic alternative to classical acylation methods, reducing the production of toxic metal waste. Different directing groups and acyl sources are being studied for this purpose, although further development is required to face mainly selectivity problems in order to be applied in the synthesis of more complex molecules. Selected recent developments and applications are covered in this review.
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© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Bestelakorik adierazi ezean, itemaren baimena horrela deskribatzen da:© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).