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dc.contributor.authorSanta Marina Rodríguez, Loreto
dc.contributor.authorLertxundi Iribar, Nerea
dc.contributor.authorAndiarena Villaverde, Ainara ORCID
dc.contributor.authorIrizar Loibide, Amaia
dc.contributor.authorSunyer, Jordi
dc.contributor.authorMolinuevo, Amaia
dc.contributor.authorLlop, Sabrina
dc.contributor.authorJulvez, Jordi
dc.contributor.authorBeneito, Andrea
dc.contributor.authorIbarluzea Maurolagoitia, Jesús María
dc.contributor.authorImaz, Liher
dc.contributor.authorFerrin, Maite
dc.date.accessioned2020-11-13T12:37:53Z
dc.date.available2020-11-13T12:37:53Z
dc.date.issued2020-10-22
dc.identifier.citationInternational Journal of Environmental Research and Public Health 17(21) : (2020) // Article ID 7704es_ES
dc.identifier.issn1660-4601
dc.identifier.urihttp://hdl.handle.net/10810/47947
dc.descriptionCorrección publicada en International Journal of Environmental Research and Public Health 18(12) : (2021) // Article ID 6283
dc.description.abstractFerritin status during prenatal brain development may influence the risk of attention deficit and hyperactivity disorder (ADHD) symptoms in childhood. We investigated the association of maternal ferritin in pregnancy and ADHD-like symptoms in offspring. A total of 1095 mother-child pairs from three birth cohorts of the INMA Project (Spain) were studied. Maternal plasma ferritin in pregnancy was measured at 11.57 weeks of gestation. Children′s ADHD-like symptoms at ages 4–5 years were assessed using the ADHD Rating Scale-IV. The count model of the zero-inflated Poisson regression model showed a significant inverse association between ferritin (continuous variable) and inattention, β = −0.19 (−0.32, −0.07), for boys. Comparing ferritin level by tertiles, significant differences were observed between the first tertile ([1.98, 20.92]) and the second ([20.92, 38.79]) and third tertiles ([38.79, 216.5]) (mg/L).The number of symptoms was lower for those in the third tertile, β = −0.3 (−0.55, −0.5), and for those in the second one, β = −0.37 (−0.6, −0.14). The model stratification by sex also showed this inverse association for boys only, β = −0.21 (−0.34, −0.08). No associations were found between ferritin level and hyperactivity or total ADHD symptoms. High ferritin levels during pregnancy show a protective association with child inattentive-type ADHD symptoms.es_ES
dc.description.sponsorshipGipuzkoa: This study was funded by grants from Instituto de Salud Carlos III (FIS-PI06/0867, FIS-PI09/00090 and FIS-PI13/02187), CIBERESP, Department of Health of the Basque Government (2005111093, 2009111069 and 2013111089) and the Provincial Government of Gipuzkoa (DFG06/002 and DFG08/001). Sabadell: This study was funded by grants from Instituto de Salud Carlos III (Red INMA G03/176; CB06/02/0041; PI041436; and PI081151 including support from the European Regional Development Fund (ERDF), Generalitat de Catalunya-CIRIT 1999SGR 00241, Fundació La marató de TV3 (090430). ISGlobal is a member of the CERCA Programme, Generalitat de Catalunya. Valencia: This study was funded by grants from the European Union (FP7-ENV-2011, grant number: 282957 and HEALTH.2010.2.4.5-1); Spain (ISCIII: G03/176; FIS-ERDF: PI11/01007, PI11/02591, PI11/02038, PI12/00610, PI13/1944, PI13/2032, PI14/00891, PI14/01687, PI16/1288, and PI17/00663; Miguel Servet-European Regional Development Fund CP11/00178, CP15/00025, and MSII16/00051); Generalitat Valenciana: FISABIO (UGP 15-230, UGP-15-244, and UGP-15-249); and the Alicia Koplowitz Foundation (2017); Instituto de Salud Carlos III through the projects “CP14/00108 and PI16/00261” (Co-funded by European Regional Development Fund “A way to make Europe”). Jordi Julvez holds the Miguel Servet-II contract (CPII19/00015) awarded by the Instituto de Salud Carlos III (co-funded by the European Social Fund “Investing in your future”).es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/282957es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/
dc.subjectferritin statuses_ES
dc.subjectpregnancyes_ES
dc.subjectADHD symptomses_ES
dc.subjectchildhoodes_ES
dc.titleMaternal Ferritin Levels during Pregnancy and ADHD Symptoms in 4-Year-Old Children: Results from the INMA–INfancia y Medio Ambiente (Environment and Childhood) Prospective Birth Cohort Studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.date.updated2020-11-12T14:13:34Z
dc.rights.holder2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).es_ES
dc.relation.publisherversionhttps://www.mdpi.com/1660-4601/17/21/7704/htmes_ES
dc.identifier.doi10.3390/ijerph17217704
dc.identifier.doi10.3390/ijerph18126283 (corrección)
dc.contributor.funderEuropean Commission
dc.departamentoesPsicología Social y Metodología de las Ciencias del Comportamiento
dc.departamentoeuGizarte psikologia eta portaera zientzen metodologia


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2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).