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TWEAK/Fn14 Signaling Is Required for Liver Regeneration after Partial Hepatectomy in Mice
(Public Library Science, 2014-01-09)
Background & Aims: Pro-inflammatory cytokines are important for liver regeneration after partial hepatectomy (PH). Expression of Fibroblast growth factor-inducible 14 (Fn14), the receptor for TNF-like weak inducer of ...
The E2F2 Transcription Factor Sustains Hepatic Glycerophospholipid Homeostasis in Mice
(Public Library Science, 2014-11-14)
Increasing evidence links metabolic signals to cell proliferation, but the molecular wiring that connects the two core machineries remains largely unknown. E2Fs are master regulators of cellular proliferation. We have ...
Insights Into SND1 Oncogene Promoter Regulation
(Frontiers Media SA, 2018-12-11)
The staphylococcal nuclease and Tudor domain containing 1 gene (SND1), also known as Tudor-SN, TSN or p100, encodes an evolutionarily conserved protein with invariant domain composition. SND1 contains four repeated ...
SREBP-2-driven transcriptional activation of human SND1 oncogene
(Impact Journals LLC, 2017-12-08)
Upregulation of Staphylococcal nuclease and tudor domain containing 1 (SND1) is linked to cancer progression and metastatic spread. Increasing evidence indicates that SND1 plays a role in lipid homeostasis. Recently, it ...
Elite Swimmers’ Training Patterns in the 25 Weeks Prior to Their Season’s Best Performances: Insights Into Periodization From a 20-Years Cohort
(Frontiers Media, 2019-04-10)
Background: This study investigated the periodization of elite swimmers' training over the 25 weeks preceding the major competition of the season.
Methods: We conducted a retrospective observational study of elite male ...
Training and Competition Readiness in Triathlon
(MDPI, 2019-04-29)
Triathlon is characterized by the multidisciplinary nature of the sport where swimming, cycling, and running are completed sequentially in different events, such as the sprint, Olympic, long-distance, and Ironman formats. ...
Silencing of Sinusoidal DDR1 Reduces Murine Liver Metastasis by Colon Carcinoma
(Nature, 2020-10-27)
Liver metastasis depends on the collagenous microenvironment generated by hepatic sinusoidal cells (SCs). DDR1 is an atypical collagen receptor linked to tumor progression, but whether SCs express DDR1 and its implication ...
Effects Of Combined High-Intensity Aerobic Interval Training Program And Mediterranean Diet Recommendations After Myocardial Infarction (INTERFARCT Project): Study Protocol For A Randomized Controlled Trial
(Biomed Central, 2018-03-02)
Exercise therapy has long been used for rehabilitation purposes after myocardial infarction (MI) and the benefit of regular physical exercise is also well-established. High-intensity interval training (HIIT) has been ...
Physical Activity, Sedentary Behavior, and Sleep Quality in Adults with Primary Hypertension and Obesity before and after an Aerobic Exercise Program: EXERDIET-HTA Study
(MDPI, 2020-08-17)
Background: The purposes of the study were to: analyze, by objective (accelerometry) and subjective (International Physical Activity Questionnaire, IPAQ) methodologies, the physical activity (PA) and sedentary behavior ...
BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque
(MDPI, 2020-12-09)
Carotid atherosclerotic plaque rupture can lead to cerebrovascular accident (CVA). By comparing RNA-Seq data from vascular smooth muscle cells (VSMC) extracted from carotid atheroma surgically excised from a group of ...