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Now showing items 11-18 of 18

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The Role of the Subthalamic Nucleus in L-DOPA Induced Dyskinesia in 6-Hydroxydopamine Lesioned Rats 

Aristieta Arbelaiz, Asier; Azkona Mendoza, Garikoitz; Sagarduy Crespo, Ainhoa; Miguélez Palomo, Cristina; Ruiz Ortega, José Ángel; Sánchez Pernaute, Rosario; Ugedo Urruela, Luisa (Public Library of Science, 2012-08-06)
L-DOPA is the most effective treatment for Parkinson's disease (PD), but prolonged use leads to disabling motor complications including dyskinesia. Strong evidence supports a role of the subthalamic nucleus (STN) in the ...
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Early Functional Deficit and Microglial Disturbances in a Mouse Model of Amyotrophic Lateral Sclerosis 

Gerber, Yannick Nicolas; Sabourin, Jean Charles; Rabano, Miriam; Vivanco, Maria dM; Perrin, Florence (Public Library of Science, 2012-04-25)
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by selective motoneurons degeneration. There is today no clear-cut pathogenesis sequence nor any treatment. However growing ...
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GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease 

Kamphuis, Willem; Mamber, Carlyn; Moeton, Martina; Kooijman, Lieneke; Sluijs, Jacqueline A.; Jansen, Anne H. P.; Verveer, Monique; De Groot, Lody R.; Smith, Vanessa D.; Rangarajan, Sindhoo; Rodríguez Arellano, José Julio; Orre, Marie; Hol, Elly M. (Public Library of Science, 2012-08-13)
Glial fibrillary acidic protein (GFAP) is the main astrocytic intermediate filament (IF). GFAP splice isoforms show differential expression patterns in the human brain. GFAPδ is preferentially expressed by neurogenic ...
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Ancient DNA from Hunter-Gatherer and Farmer Groups from Northern Spain Supports a Random Dispersion Model for the Neolithic Expansion into Europe 

Hervella Afonso, Montserrat; Izagirre Arribalzaga, Neskuts; Alonso Alegre, Santos; Fregel, Rosa; Alonso, Antonio; Cabrera, Vicente M.; De la Rúa Vaca, Concepción (Public Library of Science, 2012-04-25)
Background/Principal Findings: The phenomenon of Neolithisation refers to the transition of prehistoric populations from a hunter-gatherer to an agro-pastoralist lifestyle. Traditionally, the spread of an agro-pastoralist ...
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GmcA Is a Putative Glucose-Methanol-Choline Oxidoreductase Required for the Induction of Asexual Development in Aspergillus nidulans 

Echeveste Juárez, Oier; Herrero García, Erika; Cortese, Marc S.; García Aguirrezabala, Aitor; Oiartzabal Arano, Elixabet; De los Ríos, Vivian; Ugalde Martínez, Unai; Espeso, Eduardo A. (Public Library of Science, 2012-07-05)
Aspergillus nidulans asexual differentiation is induced by Upstream Developmental Activators (UDAs) that include the bZIP-type Transcription Factor (TF) FlbB. A 2D-PAGE/MS-MS-coupled screen for proteins differentially ...
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PAnalyzer: A software tool for protein inference in shotgun proteomics 

Prieto Agujeta, Gorka; Aloria Escolastico, Kerman; Osinalde Moraleja, Nerea; Fullaondo Elordui-Zapaterieche, Asier; Arizmendi Bastarrika, Jesús María; Matthiesen, Rune (BioMed Central, 2012-11-05)
Background Protein inference from peptide identifications in shotgun proteomics must deal with ambiguities that arise due to the presence of peptides shared between different proteins, which is common in higher eukaryotes. ...
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ICGE: an R package for detecting relevant clusters and atypical units in gene expression 

Irigoyen Garbizu, Itziar; Sierra Araujo, Basilio; Arenas Solá, Concepción (BioMed Central, 2012-02)
Background: Gene expression technologies have opened up new ways to diagnose and treat cancer and other diseases. Clustering algorithms are a useful approach with which to analyze genome expression data. They attempt to ...
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Prognostic Role of Host Cyclooxygenase and Cytokine Genotypes in a Caucasian Cohort of Patients with Gastric Adenocarcinoma 

García-González, María Asunción; Nicolás-Pérez, David; Lanas, Ángel; Bujanda Fernández de Pierola, Luis; Carrera, Patricia; Benito, Rafael; Strunk, Mark; Sopeña, Federico; Santolaria, Santos; Piazuelo, Elena; Jiménez, Pilar; Campo, Rafael; Espinel, Jesús; Manzano, Marisa; Geijo, Fernando; Pellisé, María; González-Huix, Ferrán; Espinós, Jorge; Zaballa, Manuel; Titó, Llúcia; Barranco, Luis; Pazo, Roberto; Quintero, Enrique (Public Library of Science, 2012-09-28)
Background: Genetic factors influencing the prognosis of gastric adenocarcinoma (GAC) are not well known. Given the relevance of cytokines and other pro-inflammatory mediators in cancer progression and invasiveness, we ...
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AuthorBujanda Fernández de Pierola, Luis (2)Gerber, Yannick Nicolas (2)Perrin, Florence (2)Sabourin, Jean Charles (2)... View MoreDepartamento (cas.)Genética, antropología física y fisiología animal (4)Neurociencias (3)Bioquímica y biología molecular (2)Medicina (2)... View MoreDepartamento (eus.)Genetika,antropologia fisikoa eta animalien fisiologia (4)Neurozientziak (3)Biokimika eta biologia molekularra (2)Medikuntza (2)... View MoreSubject
BIOCHEMISTRY AND MOLECULAR BIOLOGY (18)
AGRICULTURAL AND BIOLOGICAL SCIENCES (16)MEDICINE (16)COMPUTER SCIENCE APPLICATIONS (2)... View MoreDate Issued
2012 (18)
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eng (18)

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